403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
223 citations,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
25 citations,
September 2014 in “Pharmacotherapy” Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.
23 citations,
October 2016 in “Journal of Midwifery & Women's Health” The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.
16 citations,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
11 citations,
September 2012 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
6 citations,
April 2019 in “Endocrinology and Metabolism Clinics of North America” Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.
6 citations,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.
28 citations,
October 2018 in “Clinical Obstetrics and Gynecology” Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
13 citations,
January 2015 in “Stem cells international” Mesenchymal Stem Cells (MSCs) are promising for multiple therapies, but more research is needed to fully understand and optimize their use.
2 citations,
March 2001 in “Environmental Health Perspectives” Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
3 citations,
March 2019 in “Post Reproductive Health” Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
3 citations,
June 2018 in “Bioorganic & medicinal chemistry” Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
854 citations,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
21 citations,
June 1990 in “British Journal of Dermatology” Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
December 2017 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” Topical minoxidil may help regrow hair after permanent hair loss from chemotherapy.
129 citations,
February 2006 in “Andrology” Men with low testosterone should be carefully evaluated and monitored before and during treatment.
49 citations,
February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
15 citations,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
5 citations,
December 2014 in “Polish Journal of Public Health” Zinc is essential for many body functions and imbalances can lead to health problems.
April 2019 in “Endocrinology and Metabolism Clinics of North America” Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
89 citations,
November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
3 citations,
December 2011 in “Pediatric Dermatology” The patient's long-term hair loss was caused by leukemia treatments and low estrogen levels, worsened by her genetic tendency for hair loss.
April 2024 in “Nepal journal of dermatology, venereology & leprology” Vitamin D is important for skin health and can help treat and prevent various skin conditions.
271 citations,
September 2008 in “Nutrition reviews” Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
76 citations,
January 2017 in “World Journal of Stem Cells” Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
61 citations,
January 2017 in “Human Reproduction Open” The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.
34 citations,
January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.