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This review discusses how the HSD3B1(1245C) genotype may impact androgen physiology and the progression of castration-resistant prostate cancer, and does not report new experimental results.

This study identified molecular differences between dysplastic nevi and common melanocytic nevi, including altered keratinocyte differentiation, increased hair follicle-related molecule expression, and distinct immune microenvironment characteristics in dysplastic nevi.

This study found that both bFGF and herbal extracts significantly induced proliferation in human hair follicle mesenchymal stem cells, suggesting their potential for promoting hair growth.

The researchers reported that DHT-inducible DKK-1 may play a significant role in DHT-driven balding by inhibiting hair follicle cell growth and promoting apoptosis in androgenetic alopecia.

This study found that C57BL/6 mice and Sprague–Dawley rats show distinct distributions of eccrine sweat glands and hair follicles in their volar skin, suggesting these models should be selected according to research focus on skin appendages.

This study found that BMP signaling is involved in regulating melanogenesis, pigment transfer, and melanocyte migration, contributing to our understanding of skin pigmentation mechanisms.

This chapter hypothesizes that vitamin D signaling in the skin may suppress UV radiation-induced epidermal tumor formation, reviewing potential mechanisms without reporting new clinical results.

The study observed that the tumor suppressor activity of bone morphogenetic proteins in mouse skin epithelium depends on Noggin levels, inhibiting Wnt and Shh signaling pathways to prevent tumor initiation and progression.

In this study, Gsdma1/2/3 knockout mice showed reduced epidermal hyperplasia and inflammation when induced by PMA, which was attributed to decreased EGFR-Stat3/Akt signaling due to a decrease in related ligands.

This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.

In this study, significant upregulation of the genes SFRP2 and PTGDS was found in bald hair follicles of female pattern hair loss patients compared to non-bald follicles, suggesting these genes may be biomarkers and play a role in hair loss for this condition.

This research suggests that the vitamin D receptor may regulate hair follicle cycling and provide genoprotection against skin carcinogenesis through a mechanism independent of 1,25-dihydroxyvitamin D3, based on evidence from mouse models.

This study found that activating Wnt/beta-catenin signaling in hair follicles is sufficient to induce adipocyte generation in the dermis, affecting both hair follicle stem cell activation and adipocyte differentiation.

In this study, researchers developed a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing that basal cell carcinoma likely originates from hair follicles and involves expansion of specific fibroblast subpopulations found in healthy skin.

This report discusses the challenges of interpreting bone mineral density in transgender individuals undergoing hormone therapy and highlights the lack of guidelines for assessing fracture risk or BMD results in this population.

This study identified CD201+ fibroblast progenitors in mouse skin that regulate wound healing through differentiation into specialized cell types, with retinoic acid and hypoxia influencing this process.

This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.

This review summarizes current evidence on the use of contact immunotherapy, excluding alopecia areata, for various skin diseases, discussing its safety, efficacy, and the underlying mechanisms as reported from studies in the PubMed database.

This study suggests that Bim and Puma proteins play a role in hair follicle development and maintenance, although they only partially overlap with apoptosis during normal hair cycle stages.

This study found that chronic UVR exposure in mice and humans leads to a permanent loss of papillary fibroblasts in the upper dermis, which is associated with changes in the extracellular matrix.

This study shows that inhibiting anti-apoptotic proteins BCL-W and BCL-XL can specifically induce apoptosis in senescent cells, suggesting a potential strategy for treating age-related pathologies.

The study found that dermal EZH2 plays a crucial role in coordinating dermal fibroblast differentiation and epidermal development by modulating Wnt/β-catenin and retinoic acid signaling.

This study found that CD133-positive dermal papilla cells significantly enhanced hair growth in mice compared to CD133-negative cells, suggesting their potential for improving human hair follicle engineering.

In this study, researchers developed a new hydrogel incorporating fibroblast growth factor 21 that improved wound healing in diabetic mice by reducing inflammation and enhancing skin repair, suggesting strong potential for future clinical application in diabetic wound management.

This study found that Bnip3L and caspase-12 were differentially expressed during the first catagen stage of mouse hair follicle development under normal physiological conditions.

This study reports that analyzing the clinical manifestations of different genetic variants in EBS families helps predict disease progression and severity, guide complication risk assessment, and plan necessary medical care.

The testes significantly contribute to vitamin D metabolism and may affect male reproductive health and conditions like hair loss.

In this study on a mouse model of vitiligo, NB-UVB/ADSC combination therapy improved oxidative stress and calcium homeostasis, but the protective effect was reversed by inhibiting Nr2 signaling.