June 2013 in “Annals of the rheumatic diseases” This study concluded that while methotrexate-related adverse events were infrequent in early rheumatoid arthritis patients taking adalimumab, some increased with higher methotrexate doses, suggesting use of the lowest effective dose.
136 citations
,
April 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.
104 citations
,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
30 citations
,
June 2008 in “Dermatologic Surgery” In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.
27 citations
,
January 2006 in “Dermatologic Surgery” This study found that the SAFE System may improve follicular unit extraction by reducing follicle transection rates and broadening patient eligibility, with only minor adverse reactions reported.
24 citations
,
September 2014 in “Drug Delivery” This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.
14 citations
,
May 2013 in “Experimental Dermatology” This study found that the modified wash test was generally more effective than TrichoScan® for diagnosing hair loss, particularly telogen effluvium, though both methods showed only fair concordance with clinical diagnosis.
9 citations
,
September 2019 in “Clinical, Cosmetic and Investigational Dermatology” In this case report, the authors observed that scalp injection of autologous adipose tissue had a positive effect on hair growth in a patient with trauma-related alopecia, suggesting it might be a promising treatment for alopecia.
5 citations
,
January 2018 in “Skin Pharmacology and Physiology” This study found that a high sesquiterpene C. aeruginosa extract significantly reduced axillary hair growth in women compared to placebo with no apparent adverse effects.
1 citations
,
June 2020 in “Journal of AOAC INTERNATIONAL” This study reports that two novel chromatographic methods demonstrated high sensitivity and selectivity for determining aminexil, niacinamide, and pyridoxine HCl in a laboratory-prepared mixture and hair tonic preparation.
September 2024 in “International Journal of Research and Review” This study found that Wiesbaden Dilution 30C significantly reduced hair fall in 76.66% of Telogen Effluvium patients, with 23 out of 30 experiencing notable improvement and new hair growth without adverse effects.
June 2016 in “Annals of the rheumatic diseases” This study found that methotrexate, when administered according to current recommendations, effectively manages rheumatoid arthritis for many patients in Poland, although regular monitoring is necessary due to possible adverse effects.
December 2015 in “Vascular Pharmacology” Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.
46 citations
,
January 2009 in “Textile Research Journal” This study presents a DNA-analytical method that can reliably identify and differentiate cashmere, fine wool, yak, and camel hair fibers in both untreated and processed samples.
34 citations
,
July 2010 in “Expert Opinion on Drug Delivery” This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.
155 citations
,
August 1991 in “Journal of The American Academy of Dermatology” This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
81 citations
,
August 2011 in “Journal of The American Academy of Dermatology” In this study, latanoprost significantly increased hair density in young men with mild androgenetic alopecia after 24 weeks, suggesting it may stimulate hair follicle activity and treat hair loss.
30 citations
,
July 2001 in “BJUI” Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.
23 citations
,
September 2016 in “BMC musculoskeletal disorders” This study suggests that methotrexate use among rheumatoid arthritis patients is associated with patient-reported side effects and tolerability issues that may not be fully recognized by physicians.
12 citations
,
August 2020 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that most chronic alopecia areata patients treated with azathioprine, methotrexate, or cyclosporine continued treatment for at least 12 months, often requiring concurrent low-dose prednisolone.
8 citations
,
September 2023 in “Advanced Pharmaceutical Bulletin” In a double-blind clinical trial, this study found that a gel containing chitosan-coated spironolactone nanoparticles effectively reduced acne lesions over 8 weeks without adverse skin effects, suggesting potential for enhanced acne treatment through targeted skin delivery.
8 citations
,
January 2019 in “Acta dermato-venereologica” In this study, methotrexate effectively treated juvenile localized scleroderma in most cases, with few patients showing resistance and no identifiable profile for these resistant individuals.
7 citations
,
December 1987 in “Fertility and sterility” The vellus index is a simple, quick, and reliable method to assess and monitor hair growth, especially in hirsutism.
5 citations
,
September 2016 in “Dermatologic Therapy” This paper reports three cases of hair transplantation using Feily's method, which showed unusual long-lasting dark areas on the scalp, suggesting more than 24 hours of caution might be needed to prevent necrosis.
5 citations
,
June 2012 in “Journal of Cosmetic and Laser Therapy” This study found that combining topical finasteride with IPL + RF hair removal significantly reduced unwanted facial hair in women after six months compared to placebo.
2 citations
,
April 2021 in “Journal of Cosmetic Dermatology” This study found that androgenetic alopecia significantly impacts young men's quality of life, affecting their self-esteem and daily functioning, and highlights the need for a specialized assessment tool.
2 citations
,
October 2020 in “Dermatologic Therapy” This study found that a topical herbal solution significantly increased hair diameter and density in men with androgenetic alopecia compared to minoxidil after 36 weeks of treatment.
1 citations
,
January 2026 This study outlined modern approaches for using cosmeceuticals in trichology, emphasizing evidence-based medicine, personalized care, and patient safety. It proposed the H.A.I.R. model as a universal algorithm for trichological programs and suggested new educational and practical tools for specialists in trichology and aesthetic medicine.
1 citations
,
October 2024 in “Dermatology Practical & Conceptual” In this double-blind randomized controlled trial, both rosemary extract lotion and 2% ketoconazole lotion were effective for treating scalp seborrheic dermatitis, but rosemary lotion reduced itching more significantly, while ketoconazole was more effective in reducing dandruff.
June 2025 in “World Journal of Medical Oncology” In this study, researchers explored the use of new biobased compounds and gels as potential treatments for skin cancer, finding that these biological materials may be significant in limiting and eliminating skin tumors alone or when combined with other methods.