1 citations
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January 2010 in “Springer eBooks” Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
January 2020 in “Asian journal of applied science and technology” This source provides an overview of the dietary recommendations for macronutrient intake and the benefits of plant-based diets, including meeting essential amino acid needs through combining plant proteins and the advantages of consuming complex carbohydrates and adequate fiber for health.
March 2014 in “CRC Press eBooks” Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.
January 2021 in “Middle East journal of applied sciences” This article discusses the widespread issue of zinc deficiency affecting plant, animal, and human health, and reports no new clinical results; the authors emphasize the need for adequate zinc availability in agriculture and nutrition.
59 citations
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May 2017 in “Scientific reports” This study found that ZDHHC13 deficiency in mice is associated with abnormal liver function, lipid metabolism issues, and impaired mitochondrial function, highlighting ZDHHC13's regulatory role in liver metabolism.
3 citations
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November 2021 in “Applied Microscopy” This article presents a comprehensive overview of hair microscopy techniques and their diagnostic potential for systemic and cutaneous disorders, emphasizing its usefulness in resource-limited settings and highlighting the underutilization of this non-invasive method due to lack of awareness.
This systematic review found no consistent evidence supporting the effectiveness of biotin supplementation for alopecia treatment unless there is a documented deficiency.
May 2025 in “Health Science Reports” This study reported that applying Serum WS Biotin, a water-soluble form of D-Biotin, daily for 3 months significantly reduced hair shedding and increased hair strength in volunteers with moderate to excessive hair shedding, while showing good skin compatibility.
July 2025 in “Cosmoderma” In this study, a 90-day course of a plant-based supplement significantly improved hair density, skin hydration, and nail growth among participants with dermatological concerns, while also reducing hair fall and pigmentation, without adverse effects.
October 2023 in “International Journal of Cosmetic Science” In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.
July 2026 in “IntechOpen eBooks” This research highlights the crucial roles of B vitamins in metabolism, neurological processes, and DNA functions, and describes emerging therapies that enhance vitamin absorption and therapeutic potential.
August 2023 in “Natural Resources for Human Health” This paper offers a detailed overview of B vitamins, detailing their importance for energy, cognition, and metabolism, conditions leading to their deficiencies, symptoms of deficiencies, and the foods rich in these essential nutrients.
1 citations
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January 2015 in “Hair therapy & transplantation” This investigation found that certain supplements, particularly whey protein isolate, growth hormones, and anabolic steroids, can negatively impact hair loss by affecting biochemical pathways.
September 2025 in “Indian Journal of Psychiatry” This study found that individuals taking valproate had a higher incidence of hair loss and reported an association between valproate levels, reduced biotinidase activity, and hair loss, compared to a control group.
August 2025 in “International Journal for Vitamin and Nutrition Research” This review highlights the important role of the vitamin B complex in enhancing tissue repair, reducing inflammation, and improving surgical outcomes in plastic and reconstructive procedures by supporting cellular processes such as mitochondrial efficiency, neurotransmitter biosynthesis, and wound healing pathways.
19 citations
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January 2019 in “International Journal of Trichology” This consensus paper reviews expert opinions on treating telogen effluvium but reports no new clinical findings.
21 citations
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August 2024 in “Journal of Clinical Medicine” This review highlights that malnutrition, including deficiencies in proteins and micronutrients, may exacerbate allergic conditions like dermatitis and asthma by promoting inflammation, while adequate micronutrient intake supports regulatory immune responses.
Men need essential vitamins like D, B Complex, and A for health, and should consult doctors for personalized advice.
September 2026 in “Journal of Cosmetic Dermatology” This scoping review reports that preclinical studies suggest omega fatty acids may promote hair follicle growth, but clinical evidence is mixed, with no support for their standalone use in treating alopecia.
1 citations
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June 2019 in “Current developments in nutrition” This study observed that a combination of arginine silicate complex and magnesium biotinate significantly improved hair and nail growth in rats.
78 citations
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January 2017 in “Skin appendage disorders” This review discusses the use of biotin for hair and nail growth, noting clinical improvement in cases with existing pathologies, but concludes there is insufficient evidence supporting its benefits for healthy individuals.
158 citations
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May 1968 in “The journal of nutrition/The Journal of nutrition” This study found that severe zinc deficiency induced in weanling rats led to growth retardation, hair issues, and dermal lesions, all of which were completely reversed by zinc supplementation.
75 citations
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May 2013 in “Journal of the American Academy of Dermatology” This review examines skin symptoms, diagnosis, and treatment of zinc deficiency in children, proposing a classification system but reporting no new clinical results.
September 2025 in “Journal of Pakistan Association of Dermatologists” This study compared the effectiveness of adding Biotin supplements to PRP treatment against using PRP alone for androgenetic alopecia patients and found no additional benefits in hair regrowth when Biotin was included.
72 citations
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October 2010 in “Journal of The American Academy of Dermatology” This study concluded that iron deficiency is common among women but not more prevalent in those with female pattern hair loss or chronic telogen effluvium compared to control subjects without hair loss.
3 citations
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May 2014 in “InTech eBooks” This review discusses the genetic and androgen-related factors in androgenetic alopecia, highlighting a specific polymorphism in the AR protein associated with male pattern hair loss, and reports no new clinical results.
4 citations
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August 2018 in “Journal of The American Academy of Dermatology” This response article concurs with Dr. Lipner's critique that biotin supplementation is largely unsupported for routine use in dermatological conditions, with evidence mostly limited to case reports.
11 citations
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January 2014 in “The Scientific World Journal” This study found that Cynatine HNS significantly improved hair and nail health in women after 90 days compared to placebo.
October 2025 in “International Journal For Multidisciplinary Research” This study describes a case where a patient with Vitamin B12 deficiency symptoms achieved increased serum B12 levels and symptom relief through treatment with Amyron syrup and Amlycure DS capsules, rather than traditional B12 supplements.
December 2015 in “Basrah Journal of veterinary Research” In this study, researchers found that most buffaloes in Basrah, Iraq, suffered mineral deficiencies, especially in zinc, cobalt, copper, and sulfur, with outdoor grazing buffaloes displaying more severe deficiencies than those kept indoors.