The Effect of a Combination of an Arginine Silicate Complex and Magnesium Biotinate on Hair and Nail Growth in Rats

The study aimed to evaluate the effects of a novel combination of an arginine silicate complex (ASI) and magnesium biotinate (MgB) on hair and nail growth in rats. Twenty-one female Sprague-Dawley rats were divided into three groups: a control group, a group receiving a low dose of ASI and MgB, and a group receiving a high dose of ASI and MgB. Over six weeks, the rats were treated daily, and their hair and nail growth were measured. The results showed that both treatment groups experienced greater hair growth compared to the control, with the high dose group showing the most significant improvement. Hair density and the percentage of hair follicles in the anagen phase were higher in the treatment groups, particularly in the high dose group. Additionally, blood levels of vascular endothelial growth factor, which is associated with hair growth, were higher in the treatment groups. Nail growth was also faster in the high dose group. The study concluded that the combination of an arginine silicate complex and magnesium biotinate promotes hair and nail growth in rats.