59 citations,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
18 citations,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
117 citations,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
1 citations,
October 2019 in “International journal of contemporary pediatrics” A 12-year-old boy with twenty nail dystrophy, a condition affecting all nails, was treated conservatively due to its self-limiting nature and good prognosis.
1 citations,
July 2017 in “Clinical research in dermatology” Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.
May 2023 in “Journal of Cosmetic Dermatology” Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.
13 citations,
September 2022 in “Frontiers in immunology” Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
10 citations,
August 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Actinic superficial folliculitis is a unique skin condition caused by intense heat and sweating.
14 citations,
August 2020 in “Journal of cosmetic dermatology” Experts recommend using PN-HPT™ for skin rejuvenation in various body areas but have less agreement on initial facial treatment cycles.
April 2008 in “Expert review of dermatology” Mutations in the P2RY5 gene cause hereditary woolly hair.
32 citations,
June 2015 in “PLOS ONE” Olive leaf compound oleuropein helps grow hair in mice.
12 citations,
November 2014 in “Bioscience, Biotechnology, and Biochemistry” Genetically modifying a bacteria and changing its growth conditions significantly increased the production of a chemical called dipicolinic acid.
11 citations,
April 2013 in “SpringerPlus” Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
82 citations,
December 2015 in “Nanomedicine” Nanoparticle systems make cancer treatment less toxic.
1 citations,
January 2016 in “Asian-Australasian journal of animal sciences” The protein Gnαs is found more in black mice than white mice and may influence their coat color.
36 citations,
September 2011 in “British Journal of Dermatology” White hair grows thicker and faster than black hair due to higher activity of growth-related genes and proteins.
9 citations,
October 2018 in “Journal of Cosmetic and Laser Therapy” Using methods like lasers and microneedling with drugs can improve hair regrowth for alopecia, but more research is needed on safety and best practices.
134 citations,
January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
124 citations,
January 2012 in “Journal of Allergy and Clinical Immunology” Endocannabinoids help control mast cell activity in human skin.
81 citations,
February 1997 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by activating PGHS-1.
29 citations,
December 2003 in “Teratology” Minoxidil use during pregnancy may cause fetal harm.
August 2023 in “Scientia Pharmaceutica” Color changes in Minoxidil hair products do not affect their effectiveness.
December 2021 in “Medicina estética” Serenoa repens may help treat hair loss but is less effective than common medications and needs more research to confirm its effectiveness.
6 citations,
December 2022 in “Cell reports” Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
82 citations,
July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
6 citations,
August 1993 in “Archives of Dermatology” A woman's hair changed to a dry, tangled texture that's hard to comb after treatment with spironolactone, suggesting the medication might cause such hair changes.
29 citations,
March 2014 in “PloS one” Astragaloside IV may help prevent hair loss by blocking a specific pathway that leads to cell death.
3 citations,
March 2014 in “Veterinary dermatology” Norwegian puffin dogs have a unique type of hair loss that often doesn't get better on its own and responds well to ciclosporin treatment.
293 citations,
November 2011 in “Nature” The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
17 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Autoimmune and metabolic issues are linked, and treating one may worsen another.