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This study found that topical bortezomib increased cell proliferation in hair follicles and sebaceous glands in mice and may activate hair keratin gene expression through GATA-3 transcription factors.

In this study, researchers found that Biofield Energy Healing Treatment significantly increased the proliferation of human hair follicle dermal papilla cells in vitro, suggesting potential hair growth benefits.

This study found that porcine skin serves as a reliable model for studying drug absorption into human hair follicles, showing a strong correlation in follicular drug absorption between porcine and human skin.

This paper discusses topical drug delivery targeting the pilosebaceous unit for skin diseases and cosmetic purposes, emphasizing formulation choice and drug physicochemical properties but reports no new findings.

This abstract reviews recent findings on the biology of isolated micrografts in hair restoration, emphasizing factors that enhance micrograft viability, but it does not report new experimental results.

This study developed and tested Bicalutamide-loaded lipid vesicles in dissolving microarray patches for topical application, finding that they effectively deliver Bicalutamide through murine skin while maintaining a favorable safety profile, suggesting potential to improve treatments for androgenetic alopecia.

This study found that bimatoprost, when applied daily at a 0.03% concentration, promoted significant hair growth in C57/black 6 mice, including earlier and faster regrowth of shaved fur.

This study found that keratin films made from human hair can potentially substitute for human nail plates in drug permeability studies, but they show higher sensitivity to penetration enhancers compared to bovine hooves.

This review discusses the enhancement of drug penetration through hair follicles and reports no new clinical results while noting the potential for future research on controlled drug release methods.

This study found that 5-bromo-3,4-dihydroxybenzaldehyde (BDB) promoted hair growth in rat vibrissa follicles by activating Wnt/β-catenin and autophagy pathways and inhibiting the TGF-β pathway in dermal papilla cells.

Iodine is absorbed by hair just below the skin surface.

This article presents a biochemical model to explain how drug molecules are incorporated into hair, highlighting factors such as drug melanin affinity and the role of physico-chemical properties.

In a laboratory setting, this study found that Biotrinine® dry extract activated hair follicle growth pathways and increased certain growth factor secretions in human dermal papilla cells, suggesting potential benefits for treating chronic hair loss.

This study found that intradermal injections of group B vitamins and cystin B6 complex improved scalp circulation, supported hair growth, and reduced hair loss in patients with diffuse alopecia.

In this study, penetration of FA-PLGA nanoparticles into hair follicles was observed in excised dog, rat, and porcine skin, with the deepest penetration in porcine skin, suggesting its similarity to human skin for drug delivery studies.

This study found that overexpression of betacellulin in transgenic mice delayed hair follicle morphogenesis and cycling, increased keratinocyte proliferation, and enhanced wound angiogenesis without affecting wound healing strength.

This study presented a new two-dimensional model that successfully predicts transdermal permeation of caffeine, highlighting the significant role of the follicular pathway in increasing systemic bioavailability.

This study found that vesicles formed with behenyltrimethylammonium chloride, stearic acid, and hinokitiol significantly improved skin permeation of hinokitiol in vitro, which may aid in hair growth promotion.

This review discusses recent advancements in cutaneous drug delivery technologies and the potential of transfollicular pathways for improved treatment of skin conditions, but reports no clinical results.

Using molecular dynamics simulations, this study explored the uptake processes of JAK inhibitors on stratum corneum and hair follicle membranes, revealing a unique interaction mechanism in the hair follicle and offering insights into transdermal drug delivery pathways.

This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.

This study found that lipid extraction increased water diffusion in wool and hair fibers; the effect was more pronounced in hair, indicating lipids are crucial for water permeability.

This study visualized mitochondrial metabolism in cultured bovine hair follicles and plucked human hairs, finding that ROS and mitochondrial polarization correlate in specific hair follicle regions, particularly near keratin deposition sites.

This study found that dietary pyridoxine increased hair follicle density in Rex rabbits by activating PI3K/Akt, Wnt, and Notch signaling pathways, which may promote hair growth and delay telogen onset.