January 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study observed that male patients with alopecia areata had elevated serum levels of HSP70 and IL-15, with levels increasing alongside disease severity, suggesting these markers are strongly associated with the disease's pathogenesis.
August 2025 in “BMC Pharmacology and Toxicology” The LTF gene may help predict and manage nonspecific orbital inflammation.
July 2025 in “Journal of Investigative Dermatology” This study found that both desmoglein-specific and non-desmoglein autoantibodies may play active roles in Pemphigus vulgaris pathogenesis, with HLA genetics influencing autoimmune specificity.
July 2025 in “Journal of Education Health and Sport” This review found that androgenetic alopecia may be associated with increased risks of cardiovascular disease, metabolic disorders, and mental health impacts, suggesting its potential as a biomarker for systemic conditions.
This study observed that, among alopecia areata patients in Fujian, China, lower IgG4 levels and higher IFN-γ levels were statistically significant, suggesting their potential role as biomarkers for the condition and highlighting avenues for future therapeutic developments.
February 2025 in “East African Scholars Journal of Medical Sciences” In this study conducted at Bangabandhu Sheikh Mujib Medical University, researchers reported that males with androgenetic alopecia had significantly higher levels of serum LH, prolactin, testosterone, DHEA-S, and free androgen index, and lower levels of serum FSH and SHBG compared to those without hair loss.
August 2024 in “Journal of Biomedical Research & Environmental Sciences” This review consolidates existing research showing that lower SHBG levels are significantly associated with adverse reproductive, metabolic, and cardiovascular outcomes, suggesting its importance as a marker in managing various health conditions.
June 2024 in “Archives of dermatological research” This study observed that patients with post-COVID telogen effluvium had lower serum ferritin levels than controls, but the levels were not indicative of nonanemic iron deficiency.
April 2023 in “Cancer research” This study suggests that KRTAP2-3 may serve as a novel biomarker to identify cells in the polyaneuploid cancer cell state, which is linked to therapy resistance and poor prognosis in prostate cancer.
September 2012 in “European journal of psychotraumatology” This study presents a new LC-MS/MS method that allows for more accurate detection of seven steroid hormones in human hair, enhancing the specificity and reliability of hormone analysis in psychoneuroendocrinological research.
March 2011 in “European Urology Supplements” CEC levels may be a useful marker for predicting prostate cancer progression.
38 citations
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May 2021 in “International Journal of Infectious Diseases” This study found that lower testosterone levels in male COVID-19 patients were associated with greater disease severity and longer hospital stays.
13 citations
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September 2014 in “BMC Complementary and Alternative Medicine” Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.
2 citations
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July 2025 in “BMC Women s Health” This study confirms that many iron deficiency symptoms occur in non-anemic women, with transferrin saturation showing a strong correlation with symptom diversity, suggesting its potential as an early diagnostic biomarker.
December 2025 in “Preprints.org” This study examined dermal papilla cells from hair follicles, finding that gene expression changes linked to wound healing and stem cell activity align with hair follicle regression, which could inform strategies for hair growth and skin rejuvenation.
April 2025 in “Dermatology Practical & Conceptual” In this study, researchers observed that individuals with premature graying of hair had significantly higher LC3 gene expression compared to controls, suggesting a potential link between autophagy and the development of this condition, with LC3 gene expression as a possible independent predictor.
In this study, researchers identified an elite germplasm of the medicinal plant Eclipta alba, known for its liver disease benefits, with higher growth, yield, and wedelolactone content, suitable for large-scale cultivation to reduce strain on wild populations.
July 2024 in “Journal of Investigative Dermatology” Sex and race affect immune responses and treatment outcomes in Hidradenitis suppurativa.
70 citations
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April 2016 in “Experimental Dermatology” In this study, oral tofacitinib treatment led to significant hair regrowth and changes in skin and blood biomarkers in a patient with alopecia areata.
47 citations
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March 2017 in “Clinical, cosmetic and investigational dermatology” This review discusses the link between Parkinson's disease and dermatological disorders, highlighting that skin biomarkers may aid in the diagnosis of Parkinson's, but it reports no new clinical results.
15 citations
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January 2023 in “Antioxidants” This review discusses oxidative stress in alopecia areata pathogenesis and potential treatment strategies, reporting no new clinical results but suggesting biomarkers for oxidative stress and discussing JAK inhibitors as promising options.
9 citations
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January 2022 in “Biology” This study concluded that male mice are more susceptible to valproic acid-induced autism spectrum disorder than female mice, with noticeable differences in brain histoarchitecture and receptor protein levels.
8 citations
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April 2024 in “Psychoneuroendocrinology”
3 citations
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January 2011 in “Annals of Dermatology” This study found that EGFR inhibitors and ligands did not significantly affect the expression of inflammatory biomarkers in cultured sebocytes, except for a notable increase in IL-1 expression with EGF treatment.
2 citations
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November 2024 in “Clinical Cosmetic and Investigational Dermatology” This Mendelian randomization study suggests a causal link between higher BMI and increased risk of psoriasis, atopic dermatitis, and hidradenitis suppurativa, potentially due to elevated biomarkers such as triglycerides and C-reactive protein.
2 citations
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March 2018 in “Biotechnology Letters” In this study, researchers established three specific cell lines from Cashmere goat hair follicles and found that cytokeratin 13 might be a novel biomarker for identifying dermal sheath cells.
1 citations
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January 2018 in “AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES” In this study, the ethanol extract of Zapoteca portoricensis stem significantly reduced markers of testosterone-induced benign prostate hyperplasia in male albino rats without harming liver and kidney function.
This case report describes how anifrolumab, used beyond trial-eligible populations, led to significant clinical and serological recovery in a 45-year-old woman with organ-threatening systemic lupus erythematosus complicated by infection and resistant to conventional treatments like cyclophosphamide and rituximab.
9 citations
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May 2025 in “Stem Cell Research & Therapy” This review discusses how extracellular vesicles play a dual role in age-related diseases by contributing to both disease pathogenesis and potential therapeutic strategies through the transfer of specific molecules.
3 citations
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January 2025 in “Journal of Research in Medical Sciences” This study reported that among obese women with PCOS, neither early time-restricted eating (eTRE) alone nor combined with probiotics showed significant improvements in blood pressure, inflammatory markers, oxidative stress, or antioxidant capacity compared to a standard reduced-calorie diet.