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This study found that testosterone treatment in older hypogonadal men caused minor improvements in depressive symptoms and visuospatial memory, but overall, major cognitive benefits were not observed.

This study found that a 5-mg daily dose of transdermal testosterone cream in postmenopausal women restored testosterone levels to those typical of premenopausal women.

This article reviews guidelines for testosterone replacement therapy in late-onset hypogonadism, emphasizing the need for clear indications and appropriate testing before treatment, but provides no new research findings.

This review examines the scientific evidence on the short-term safety of testosterone therapy for treating hypoactive sexual desire disorder in women, without presenting new clinical results.

This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.

This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.

In this study, researchers observed that a significant number of women in Eket, Nigeria, have low testosterone levels, while a subset with high free testosterone may have polycystic ovary syndrome.

This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.

In this case report, a male patient with hair loss showed unusually high testosterone levels without other symptoms or supplement use; follow-up testing revealed normal levels, showcasing the importance of considering testosterone-protein binding differences and using equilibrium dialysis for accurate assessment.

This study found that methanolic extract of Cordia plathytyrsa increased testosterone levels in male rats but did not affect other evaluated metabolic parameters.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

This study observed significant inter- and intra-individual variability in serum testosterone levels among women treated with subcutaneous testosterone implants, suggesting that therapy should be guided by clinical response rather than single serum measurements.

This study found that a 400-mg dose of oral testosterone with dutasteride increases serum testosterone levels for 8–10 hours in hypogonadal men, with the nanomilled formulation unaffected by food, suggesting a practical twice-daily therapy option.

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

In this study, elevated serum levels of aldosterone and free testosterone, along with increased androgen and aldosterone receptor levels, were associated with early-onset androgenetic alopecia in female patients.

This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.

This review examines age-related changes in androgen levels in women and explores the rationale for testosterone replacement therapy, but it reports no new clinical findings.

This review discusses the impact of testosterone therapy on postmenopausal women's sexual function and well-being but notes a lack of long-term safety studies and debates on defining androgen insufficiency.

This narrative review concludes that long-term randomized controlled trials are needed to establish clear guidelines for testosterone therapy in women, given the lack of FDA-approved formulations and the variable quality of current treatments.

In this study, male-pattern baldness was strongly associated with a higher risk of keratinocyte cancers, particularly squamous cell carcinoma and melanoma, likely due to increased sun exposure on the scalp rather than androgen levels.

This review addresses the effects of testosterone on brain development and examines both the established sex differences in brain functions and the debate surrounding structural dimorphism in neuropsychiatric conditions.

This study reported the development of a novel and reliable liquid chromatographic method to measure testosterone and epitestosterone in human urine, offering sensitive detection for doping control.

This study found that testosterone therapy can enhance sexual satisfaction and mood in surgically menopausal women on oestrogen, though ongoing monitoring and research are needed to assess long-term safety and effects in other groups.

This review discusses androgen deficiency syndrome in women, its symptoms, and how androgen replacement therapy generally alleviates related issues without significant side-effects, but reports no new clinical findings.

This case report describes a woman with severe hyperandrogenism due to ovarian tumors, where surgical removal led to dramatic improvement in her diabetes control and reduced insulin requirements.

This case study concluded that weight loss is the initial recommended approach for treating secondary hypogonadism, as shown by improvements in testosterone levels and symptoms in an obese 37-year-old patient.

This study found that testosterone-enanthate increased red blood cell production and altered iron homeostasis in older hypogonadal men without being affected by finasteride, indicating these effects do not require type II 5α-reductase enzyme activity.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

This study found no difference in bone mineral density between young women with PCOS and age- and BMI-matched controls, but BMI significantly influenced BMD in women with PCOS.

This review discusses guidelines for androgen use in women and concludes that more research is needed before recommending testosterone due to insufficient evidence on safety and efficacy.