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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Energy healing treatment improved L-cysteine's stability, solubility, bioavailability, and shelf-life.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Docetaxel is safe and works well for older people with cancer, with manageable side effects.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Some nutraceuticals may help in COVID-19 prevention and treatment, but more research is needed.

Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.

Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Cannabinoids may help treat various skin conditions.

Men with certain types of baldness at age 45 may have a higher risk of colon cancer and colorectal adenoma.

Mushroom beta-glucans from Ganoderma lucidum can reduce tumor size and metastasis in cancer.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.