research TGFβ and Cancer Metastasis: An Inflammation Link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
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research Transgenic HPV11-E2 Protein Modulates URR Activity In Vivo
The E2 protein affects gene activity in hair follicles of mice.
research Identification and Characterization of Four Immune-Related Signatures in Keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research Nonalcoholic Fatty Liver Disease and Polycystic Ovary Syndrome
People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
research Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer
African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research Adrenal Mass in a 70-Year-Old Woman
A 70-year-old woman with a malignant adrenal tumor improved after surgery and radiotherapy.
research Ascorbigen Induces Dermal Papilla Cell Proliferation In Vitro, But Fails To Modulate Chemotherapy-Induced Alopecia In Vivo
Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
research COVID-19 and Hypopituitarism
COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
research Trailing the Path to Preventive Oncology
Preventing cancer involves lifestyle changes, vaccinations, early screening, and understanding cancer's molecular basis.
research Biological Activity of Antiandrogens
Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
research O-10 An Ovarian Thecoma Presenting With Post-Menopausal Virilization
Ovarian thecomas can cause virilization in postmenopausal women and are treated with surgery.
research This Month in Clinical Urology
New treatments and diagnostic methods for urological conditions show promise, but some lack sufficient accuracy for clinical use.
research Botulinum Toxin: Pearls and Pitfalls
Doctors should recognize various nail disorders, new allergens, and metabolic syndrome in patients, and use botulinum toxin carefully in aesthetic procedures.
research Update on Nail Disorders
Not all nail problems are caused by fungus, new allergens are being identified, PCOS has various treatments, and aesthetic procedures like Botox are advancing.
research Pilomatrixoma of Face Presenting as Parotid Swelling
A young woman had a rare, usually non-cancerous tumor on her face that was initially mistaken for a different condition.
research Abstracts from the 4th Annual Student Medical Summit
The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research Steroidogenesis Inhibitors Alter But Do Not Eliminate Androgen Synthesis Mechanisms During Progression to Castration-Resistance in LNCaP Prostate Xenografts
Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
research Drug Repurposing Against KRAS Mutant G12C: A Machine Learning, Molecular Docking, and Molecular Dynamics Study
Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.
research Incidence of Alopecia from Endocrine Therapies in Cancer
Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.
research Phenotypic Profiling of Parents With Cryptic Nonclassic Congenital Adrenal Hyperplasia: Findings in 145 Unrelated Families
Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.
research Male Pattern Baldness and the Risk of Prostate Cancer
Men who experienced baldness at age 20 may have double the risk of getting prostate cancer.
research The Human Hair Follicle as Sentinel for Drug Evaluation: Demonstration of Tetracycline Adhesion to Hair Follicle as Proposed Mechanism in Dysfunctional Hair Loss
Tetracycline can stick to hair follicles and potentially cause hair loss.
research Surgical Reduction of Alopecia
Scalp reduction can improve hair distribution in certain baldness cases but requires careful patient selection and understanding of facial structure.
research Presentation of a Meningioma in a Transwoman After Nine Years of Cyproterone Acetate and Estradiol Intake: Case Report and Literature Review
A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.
research Knockout of p16INK4a Promotes Aggregative Growth of Dermal Papilla Cells
Removing p16INK4a from skin cells can lead to faster and more clumped growth, which might help with hair growth.
research Risk Factors for Prostate Cancer: An Umbrella Review of Prospective Observational Studies and Mendelian Randomization Analyses
Physical activity, height, and smoking affect prostate cancer risk.
research Association Between Male Pattern Baldness and Testicular Germ Cell Tumor: A Meta-Analysis
Baldness may lower the risk of testicular cancer.