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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Testosterone's muscle-building effects do not require its conversion to DHT.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Nerves and chemicals in the body can affect hair growth and loss.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Skin fat helps with body temperature control and has other active roles in health.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.