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The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

PCOS in teen girls should be managed with lifestyle changes and sometimes medication to improve symptoms and health.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

Testosterone helps human pancreatic cells increase insulin release.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Celery extract didn't significantly boost hair growth in the gel.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Early treatment of acne is crucial to prevent scarring and psychological effects.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

Different PCOS subgroups have similar metabolic features, but those without menstrual problems have milder issues.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

People's decision-making can be influenced by their internal biological clocks, as shown by gene expression, not just self-reported preferences for morning or evening.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.

Hair in mammals likely evolved from glandular structures, not scales.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Polycystic Ovary Syndrome (PCOS) can lead to diabetes, heart disease, cancer, and mental health problems.