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The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

RTA 408 cream protects mice from radiation skin damage.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Drug addicts often have scars, skin color changes, blocked veins, and bruising, with severe ulcers from barbiturate injections.

Hydrogels could lead to better treatments for wound healing without scars.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.

HIV can cause unusual and severe skin problems that are hard to treat.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Zinc supplements can resolve skin issues caused by zinc deficiency.

Treating cystoid macular oedema in uveitis is difficult and risky.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.