Abstracts

March 1987 in “ Journal of The American Academy of Dermatology ”

spironolactone isotretinoin tetracycline estrogen cyproterone acetate benzoyl peroxide sebum excretion congenital cutaneous candidiasis topical antifungal treatments Accutane oral contraceptives antibiotics topical antifungals

TLDR Oral spironolactone and isotretinoin are effective for treating acne.

The document summarized various studies on acne treatment and related conditions. Key findings included the effectiveness of oral spironolactone in improving acne and reducing sebum excretion, as well as the benefits of isotretinoin in long-term acne management. Studies also compared treatments like tetracycline, estrogen/cyproterone acetate, and benzoyl peroxide, highlighting their impacts on acne severity and sebum production. Additionally, a case of congenital cutaneous candidiasis was reported, showing positive response to topical antifungal treatments. The document provided insights into the pathogenesis of acne and the efficacy of different therapeutic approaches.

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