1 citations
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January 2001 in “Cosmetics and toiletries” This study found that purified apple juice containing procyanidin B-2 promoted hair growth in both mouse models and human clinical trials for male pattern baldness.
3 citations
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September 2018 in “MOJ Toxicology” This review discusses the medicinal properties of Alpinia zerumbet Roxb. and highlights its potential for further research, but provides no new clinical results.
April 2025 in “Journal of Advanced Pharmaceutical Technology amp Research” In this study, researchers reported that a combination treatment of Morinda citrifolia fruit extract and Averrhoa bilimbi leaf extract at specific concentrations significantly increased hair growth and weight in rabbits compared to controls, suggesting a potential anti-hair loss effect.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
March 2025 in “Journal of the European Academy of Dermatology and Venereology” In a retrospective multicenter cohort study, this research observed that baricitinib was effective and well-tolerated in treating adult patients with alopecia areata, including those with severe cases, showing promise in improving outcomes over a 12-month period with manageable side effects.
July 2026 in “Pharmacological Research - Modern Chinese Medicine” In this study, researchers developed and optimized a smartlipid nanocarrier gel formulation of berberine that significantly reduced hair loss and promoted faster hair regrowth in a testosterone-induced hair loss model, showing potential as an effective treatment for androgenetic alopecia.
January 2020 in “Archives of Pharmacy Practice” This study found that Hibiscus rosa-sinensis leaf extract promoted hair growth in rats more effectively than its flower extract, suggesting its potential as a natural alternative for hair growth treatments.
5 citations
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January 2022 in “Molecular Medicine Reports” In this study, topical application of Korean maritime pine bark extract at 2% concentration significantly promoted hair growth in mice, suggesting its potential use for hair loss prevention or treatment.
This study found that gels containing glycyrrhizic acid and aqueous Glycyrrhiza glabra extract significantly reduced underarm hair growth in terms of area, thickness, length, and number compared to their gel bases.
5 citations
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January 2011 in “Korean Journal of Pharmacognosy” This study found that Cornus officinalis fermented with Lactobacillus rhamnosus enhanced hair regrowth in mice, outperforming a minoxidil control.
76 citations
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February 2015 in “Industrial Crops and Products” This study identified over 40 phytochemical compounds in the leaves and flowers of Bituminaria bituminosa, predominantly glycosylated flavonoids from apigenin, using advanced chromatographic techniques.
July 2024 in “Biological and Pharmaceutical Bulletin” This study found that 18-β-Glycyrrhetinic acid, a licorice component, stimulated human hair follicle cell proliferation, inhibited testosterone 5α-reductase, and suppressed TGF-β1, suggesting potential for treating androgenetic alopecia by promoting hair growth and prolonging the anagen phase.
November 2023 in “British Journal of Dermatology” Different people with severe hair loss respond to baricitinib treatment at different times, with some showing improvement early, some gradually, and others later.
August 2023 in “Apple Academic Press eBooks” This review highlights that various parts of Eclipta prostrata contain compounds with potential antioxidant, anti-inflammatory, hepatoprotective, and hair growth-promoting effects, among other activities.
June 2025 in “Clinical and Experimental Dermatology” In this case report, a 25-year-old woman with alopecia areata experienced hair regrowth after treatment with baricitinib, despite not responding to conventional treatments, with the new hair initially appearing dark brown.
33 citations
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February 2016 in “Journal of Experimental Botany” This study found that the receptor kinase RHS10 negatively regulates root hair growth in Arabidopsis thaliana by modulating growth duration and is associated with cell wall signal mediation, involving RNA catabolism and ROS accumulation.
September 2025 in “Journal of the European Academy of Dermatology and Venereology” This real-world study found that baricitinib 4 mg daily was effective in promoting hair regrowth and improving psychological well-being in Italian adults with severe alopecia areata over 48 weeks, with 63.2% of patients achieving significant hair recovery and 9.4% experiencing adverse events.
September 2023 in “Apple Academic Press eBooks” This review highlights that Salvia rosmarinus, commonly known as rosemary, possesses multiple pharmacological activities, such as antioxidant, anti-inflammatory, and anticancer effects, and is used in medicinal, cosmetic, and food products due to its rich bioactive components.
February 2026 in “The Animal Biology” In this animal study, Hirudo verbana leech extract significantly improved hair follicle regeneration and accelerated wound healing in rats, demonstrating potential as a safe and effective agent for skin repair due to its bioactive compounds with regenerative and anti-inflammatory properties.
August 2026 in “Journal of Drug Delivery Science and Technology”
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a herbal hair serum using Embelia ribes seed extract, finding it exhibited promising antifungal properties and appropriate characteristics for scalp application, indicating potential as a natural hair care product.
2 citations
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October 2020 in “Drug Discoveries & Therapeutics” This study observed that Althaea officinalis gel increased fibroblast populations, hair follicles, and vessel diameter in rat wounds, suggesting it might aid wound healing, though further clinical studies are needed.
November 2025 in “Andalas University eThesis (Andalas University)” This study found that a rosemary extract hair tonic at concentrations up to 15% effectively promotes hair growth in male Wistar rats, achieving longer and thicker hair compared to minoxidil 2%, and causing fewer side effects.
December 2024 in “Jurnal Mandala Pharmacon Indonesia” In this study, high-dose oral administration of Ramania leaf ethanol extract in Wistar rats resulted in no significant acute toxicity symptoms, though gastric ulcers and hair loss were observed. The extract is classified as non-toxic under specified guidelines, with an LD50 greater than 5000 mg/kg.
In this study, baricitinib was used as monotherapy to treat a 21-year-old woman with severe alopecia areata, resulting in significant hair regrowth and reduced alopecia severity within three months, suggesting its effectiveness and potential as a robust treatment option for this condition.
October 2023 in “Regular and Young Investigator Award Abstracts” This study found that Baricitinib significantly reduced hair loss and immune response in a mouse model of alopecia areata.
December 2021 in “Jurnal ilmiah Manuntung” This study tested a hair tonic containing gotu kola and garlic extracts on rabbits, finding that the formulation with 5% gotu kola and 0.04% garlic showed promising hair growth results and remained stable during storage.
August 2024 in “JAMA Dermatology” In this study, withdrawal of baricitinib therapy in patients with severe alopecia areata who had achieved hair regrowth led to a loss of benefit in almost all patients, suggesting that continued treatment is necessary to maintain hair regrowth.
37 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” This study found that Bokusoku extract and its compound pentagalloyl glucose inhibited testosterone metabolism and sebum synthesis, suggesting potential therapeutic use for androgen-related acne.
4 citations
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September 2013 in “Journal of biomolecular structure and dynamics/Journal of biomolecular structure & dynamics” This study suggests that caribine may enhance the interaction between CRFR and maltose binding protein, potentially offering a new approach for treating hair loss.