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Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Finasteride may cause slight depression and anxiety.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

A20 protein is crucial for normal skin and hair development.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.