research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
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research Trichoscopic Features of Frontal Fibrosing Alopecia: Results in 249 Patients
Trichoscopy helps diagnose and assess the severity of Frontal Fibrosing Alopecia.
research Alefacept for Alopecia Areata
Alefacept showed some effectiveness for alopecia areata but needs more research.
research Antidepressants Have Anti-Inflammatory Effects Relevant to Dermatology: A Systematic Review
Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Systemic Treatment for Alopecia Areata
Effective treatments for severe alopecia areata are still lacking.
research Unsuccessful Treatment of Alopecia Areata with Simvastatin/Ezetimibe: Experience in 12 Patients
Simvastatin/ezetimibe did not effectively treat severe alopecia areata and caused side effects in some patients.
research Update on the Treatment of Alopecia Areata
Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.
research A Patient With Combined Polycystic Ovary Syndrome And Autoimmune Polyglandular Syndrome Type 2
A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.
research The Effect of DNMTs and MBPs on Hypomethylation in Systemic Lupus Erythematosus
Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
research Significance of Iron Status in Hair Loss in Women
Iron deficiency might contribute to hair loss in women.
research Diagnosis, Manifestations, Laboratory Investigations, and Prognosis in Pediatric and Adult Cushing’s Disease in a Large Center in China
Children and adults with Cushing's disease show different symptoms and males have more severe cases; surgery outcomes can be predicted by certain factors.
research Treatment Pearls From Europe
European dermatologic treatments focus on lifestyle and psychosocial factors, use diverse methods like baths and climate therapy, and emphasize the importance of diet and supplements for skin health.
research Cutaneous Drug Reactions
Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
research HIV Infection Mimicking Autoimmune Disorder
A girl with symptoms like an autoimmune disorder actually had HIV and a fungal infection, which was hard to diagnose and treat, leading to her death.
research Mesenchymal Stem Cell-Derived Protein Extract Induces Periodontal Regeneration
MSC-protein helps regenerate gum tissue and bone.
research Ringworm in Dogs: Dermatophytosis and Its Impact
Ringworm is a common, contagious fungal infection in dogs that can spread to humans and requires lengthy treatment.
research Recalcitrant Widespread Alopecia Areata in a Child Treated Successfully with Oral Methylprednisolone Pulse Therapy
Oral methylprednisolone pulse therapy helped an 11-year-old regrow 80% of his hair in six months.
research TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research LFA-1 Blockade Prevents the Onset of Alopecia Areata in C3H/HeJ Mice
Blocking LFA-1 prevents hair loss in mice.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Efficacy and Safety of Topical Rosuvastatin and Melatonin vs. Placebo in Patients with Mild to Moderate Plaque Psoriasis: A Preliminary Randomized Double-Blinded Clinical Trial
Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research Intercellular Adhesion Molecule-1 and Hair Follicle Regression
ICAM-1 helps regulate hair growth cycles and skin remodeling.
research Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
research Life Sciences Discovery And Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties
Wounded skin cells can revert to stem cells and help heal.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Birt-Hogg-Dubé Syndrome: From Gene Discovery to Molecularly Targeted Therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
research Allogeneic Hair Transplantation with Enhanced Survival by Anti-ICAM-1 Antibody with Short-Term Rapamycin Treatment in Nonhuman Primates
Using an anti-ICAM-1 antibody with rapamycin improves hair transplant survival in monkeys.