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360-390 / 1000+ resultsresearch 125: Individual Severity of Alopecia Tool (SALT) score trajectories of roll-over adolescent patients with alopecia areata (AA) treated with ritlecitinib in the ongoing long-term, open-label, phase 3 ALLEGRO-LT study
research Etrasimod for alopecia areata: The scenario for a less extensive and moderate form
This study reported that etrasimod did not achieve significant improvements in hair regrowth for moderate to severe alopecia areata at 24 weeks, although it showed a dose-dependent trend and was safe and well-tolerated over 52 weeks.
research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
This study found that spaceflight may induce skin health risks in astronauts by causing DNA damage and mitochondrial dysregulation, while also identifying gene expression changes that help re-adaptation after returning to Earth.
research STRIAA (Severity TRichoscopy Index Alopecia Areata): Validation of a Novel Trichoscopic Tool for Evaluation of Alopecia Areata
This study found that the STRIAA scoring tool provides a rapid and highly reliable assessment of alopecia areata severity, showing a significant correlation with the traditional SALT score, thus enhancing clinical evaluation in patients with this condition.
research ALOPECIA AREATA
Alopecia areata's causes are unclear, treatments exist but relapses are common.
research A High Throughput LC-MS Platform for the Discovery of Autotaxin Inhibitors
In this study, researchers investigated the role of the ATX-LPA axis in asthma pathogenesis using human and mouse models and highlighted the potential for developing new ATX inhibitors as effective asthma treatments.
research Intramembrane Proteolysis of Astrotactins
This study found that astrotactin-2 undergoes unique intramembrane proteolysis during maturation, revealing specific transmembrane topologies and substrate sequence requirements for cleavage.
research Atopic diseases and the risk of alopecia areata among pre-teens and teenagers in Taiwan
This study reported that Taiwanese pre-teens and teenagers with atopic diseases, such as food allergies and asthma, had a significantly increased risk of developing alopecia areata, with the risk being 9.66 times higher compared to their peers without atopic conditions.
research Adipose derived stem cell based therapies or male/female pattern hair loss
Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
research Adipose derived stem cell based therapies or male/female pattern hair loss
Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
research Maculopapular Drug Eruption Caused by Finasteride: A Case Report
This case report identified a maculopapular rash in a 76-year-old male, occurring 2 months after starting Finasteride for prostatic hyperplasia, with clinical and histologic evidence suggesting a drug-induced skin eruption.
research Atrichia with Papular Lesions: Dermoscopy to the Rescue
This case report describes a 3-year-old boy with atrichia with papular lesions, emphasizing that dermoscopy, showing the 'cluster of stars' appearance, facilitated diagnosis without needing a skin biopsy.
research Coexistence of alopecia areata and fixed drug eruption: An uncommon isotopic phenomenon?
This case study reports a rare instance of both alopecia areata and fixed drug eruption occurring in the same area on a 40-year-old man's beard, triggered by oral paracetamol, highlighting potential shared pathogenic pathways and the isotopic phenomenon.
research Lack of efficacy of apremilast in 9 patients with severe alopecia areata
This article hypothesizes that apremilast, a phosphodiesterase 4 inhibitor, could be a targeted treatment for alopecia areata due to its ability to suppress interferon-gamma production, but reports no new clinical results.
research Let astaxanthin be thy medicine
This article discusses various potential health benefits and increasing global interest in astaxanthin but presents no new clinical results, though ongoing trials are exploring its effects on chronic diseases and other conditions.
research The Identification of multi-target Inhibitors of Wolbachia pipientis and Onchocerca volvulus by molecular simulations
This study used molecular docking simulations to identify Adapalene, Diosmin, and Azelastine as promising drugs for repurposing against Onchocerciasis by targeting Onchocerca volvulus and its endosymbiont; further research is suggested to confirm their efficacy.
research A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
research A comprehensive Review of the Morphology, Phytochemistry and Medicinal Applications of Asteraceae Family Plants.
This review discusses the diverse phytochemical constituents and medicinal applications of Asteraceae family plants, noting their significance in traditional and modern medicine, but provides no new clinical results.
research RETRACTED: Genetic association between asthma and alopecia areata: A two‐sample Mendelian randomization study
Asthma may increase the risk of alopecia areata.
research Regulatory effect of astraglus polysaccharide on proliferation of follicle stem cells and mRNA expression of its specific marker:K19 and β1 integrin
In this study with mouse follicle stem cells, astraglus polysaccharide increased markers of cell proliferation and gene expression, suggesting a potential mechanism for treating alopecia and promoting hair growth.
research Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands
This study found that the compound androstane-17-carboxamide 6 may serve as a lead for new drugs to treat BPH and prostate cancer by reducing the weight of androgen-dependent glands.
research FINASTERIDE AND PSA
This erratum addresses the long-term effects of finasteride on prostate-specific antigen levels but reports no new research findings.
research Alopecia Areata in 12 years old female treated with Oral Azathioprine: A case report and review
This case report describes the treatment of a 12-year-old female with Alopecia Areata using oral azathioprine.
research sQuiz your knowledge: Polycyclic annular plaques on the trunk following dutasteride treatment
This study identified three EDAR gene variants potentially linked to hypohidrotic ectodermal dysplasia in three Pakistani families, which could aid in genetic counseling for similar cases.
research 133 Female Post-Finasteride Syndrome: It’s Not Just A Man’s World
PFS affects some women, steroids easily bought online, hypogonadism info unreliable, low testosterone linked to CVD.
research Potential Treatment of Steroid‐Resistant Alopecia Areata Using Allogeneic Exosomes Derived From Adipose Tissue Mesenchymal Stromal Cells: A Case Report
This single-patient case study reported promising results for severe, corticosteroid-resistant alopecia areata, with treatment using exosomes derived from mesenchymal stromal cells leading to almost complete hair regrowth in 12 weeks and favorable changes in inflammatory markers, suggesting potential for further investigation.
research Dermatoscopic of pseudocyst of the scalp
Both azathioprine and betamethasone treatments help with hair regrowth in alopecia areata, but azathioprine may have fewer side effects.
research The Identification of multi-target Inhibitors of Wolbachia pipientis and Onchocerca volvulus by molecular simulations
This study used molecular docking simulations to identify Adapalene, Diosmin, and Azelastine as promising drugs for repurposing against onchocerciasis by targeting proteins in the parasite and its endosymbiont; further research is needed to confirm their efficacy.
research Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?
This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.