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Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

Early diagnosis of Trichorhinophalangeal syndrome type 1 is crucial for treatment and was achieved through clinical examination and family history.

Dupilumab helped improve skin and prevent new lesions in a child with a rare immune disorder and severe eczema.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Dogs with dermatomyositis, especially Collies and Shetland Sheepdogs, need better treatments for their skin and muscle inflammation.

New therapies are being developed that target integrin pathways to treat various diseases.

The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.

Botulinum toxin injections effectively relieve pain from cutaneous leiomyomas.

Hair loss in men is common, treatable, but not curable.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Trichoscopy is a quick and easy way to diagnose most genetic hair problems without invasive methods.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

Understanding skin structure and development helps diagnose and treat skin disorders.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Melatonin affects certain genes and pathways involved in cashmere goat hair growth.

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

Minoxidil, finasteride, and hair transplantation combined give best results for hair loss.

Minoxidil, finasteride, and hair transplantation combined give best results for hair loss.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Most hair loss in children is caused by a few common conditions and is easy to diagnose, but rare types require careful evaluation.