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Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Minoxidil boosts hair growth by activating PGHS-1.

Best hair growth results from combining finasteride and minoxidil.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Most patients with frontal fibrosing alopecia stabilized with treatment, especially younger ones, using intralesional corticosteroids and tacrolimus.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.