May 2022 in “Journal of Education, Health and Sport” This review discusses the associations between dermatological disorders and increased cardiovascular risk, emphasizing that skin conditions with chronic inflammation may elevate the likelihood of cardiovascular diseases.
658 citations
,
June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
August 2025 in “Figshare” This meta-analysis found that patients with alopecia areata, especially those with alopecia totalis or alopecia universalis, have an increased risk of cardiovascular disease, possibly due to shared immunological mechanisms and systemic inflammation. Further research is needed to confirm these findings and explore underlying mechanisms.
3 citations
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May 2013 in “PubMed” This review discusses Hutchinson-Gilford progeria syndrome, highlighting its phenotype, pathogenesis, and its potential insights into natural aging and cardiovascular diseases, but it reports no new research findings.
January 2016 in “Ankara Üniversitesi Tıp Fakültesi mecmuası” Severe hair loss (androgenetic alopecia) is linked to higher risk of heart disease (cardiovascular atherosclerosis).
July 2024 in “Heart Lung and Circulation” There may be a link between hair loss and heart disease in women, but more research is needed.
January 2018 in “Przegla̧d dermatologiczny” This research review discusses the potential link between androgenetic alopecia and increased cardiovascular risk but does not report any new experimental findings.
38 citations
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February 2009 in “Journal of The European Academy of Dermatology and Venereology” This study found that patients with severe vertex pattern androgenetic alopecia had significantly higher carotid intima-media thickness, suggesting an increased risk of subclinical atherosclerosis compared to other alopecia patterns and healthy controls.
114 citations
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January 2014 in “World Journal of Gastroenterology” This study highlights the potential increased frequency of advanced liver disease in obese PCOS patients with NAFLD and underscores the importance of lifestyle modifications as initial treatment.
This study found that early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid arteriosclerosis compared to controls.
24 citations
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January 2015 in “International Journal of Trichology” This research observed that among young men with androgenic alopecia, there was a significant association with metabolic syndrome compared to healthy controls, suggesting AGA as a potential early marker for metabolic risk.
418 citations
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June 2003 in “Endocrine Reviews” This review discusses the relationship between polycystic ovary syndrome and cardiovascular risk, noting a possible adverse impact on risk profiles and subclinical atherosclerosis but no clear increase in premenopausal cardiovascular events; it presents no new clinical results.
June 2025 in “JEADV Clinical Practice” This study found that patients with scarring alopecia have higher rates of various systemic conditions, such as vitamin D deficiency and metabolic syndrome, compared to the national averages, and noted a significant association between certain types of scarring alopecia and atherosclerotic cardiovascular disease.
1 citations
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February 2018 in “InTech eBooks” This paper discusses the need for comprehensive evaluation and management of lean polycystic ovary syndrome patients due to their unique risks, but reports no new results.
1 citations
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April 2019 in “Endokrynologia Polska” This review discusses lifestyle interventions to manage weight and reduce metabolic consequences in women with PCOS but reports no new clinical results, highlighting the need for more randomized studies.
June 2021 in “Egyptian Journal of Dermatology and Venereology” This study found that psoriasis, acne, and androgenetic alopecia are associated with an atherogenic lipid profile, suggesting an increased risk of atherosclerosis and cardiovascular disease, especially among psoriasis patients.
3 citations
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August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.
1 citations
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May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” In this study, women with androgenetic alopecia showed higher cholesterol levels and carotid artery thickness, suggesting a potential link between female AGA and cardiovascular disease.
4 citations
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January 2016 in “Annals of Dermatology” This study found that men with more advanced androgenetic alopecia had increased epicardial fat thickness, suggesting a potential link to coronary risk.
17 citations
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June 2012 in “The Anatolian journal of cardiology” This study found that increased hair graying was associated with a greater coronary atherosclerotic burden, suggesting it could serve as a risk marker for coronary artery disease independent of age.
September 2023 in “Journal of the American Academy of Dermatology” Severe alopecia areata may increase the risk of hidden artery disease.
13 citations
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November 2015 in “Blood Pressure” This study found that early-onset androgenetic alopecia, especially with a vertex pattern, may be an independent risk factor for cardiovascular disease and metabolic syndrome in men.
3 citations
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July 2024 in “Journal of Clinical Medicine” This study found that alopecia areata patients have a higher prevalence of carotid subclinical atherosclerosis, with factors such as disease duration, systemic inflammation, and insulin resistance potentially contributing to this increased risk.
10 citations
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November 2024 in “Cureus” This systematic review identified several factors contributing to increased cardiovascular risk in women with polycystic ovary syndrome, including insulin resistance, obesity, inflammation markers, and microbiota alterations linked to elevated trimethylamine-N-oxide levels.
10 citations
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November 2024 in “Nature Reviews Cardiology” Skin conditions can signal heart issues, highlighting the need for integrated care.
2 citations
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May 2017 in “Maturitas” Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
26 citations
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January 2013 in “BMJ Open” This meta-analysis reports that vertex baldness is associated with an increased risk of coronary heart disease, particularly in younger men, while no significant link was found for frontal baldness.
15 citations
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May 2010 in “Actas Dermo-Sifiliográficas” This study found that men with early-onset androgenetic alopecia had a higher prevalence of metabolic syndrome and carotid atheromatous plaques than control subjects, suggesting a need for cardiovascular screening in this group.
May 2023 in “Arteriosclerosis, thrombosis, and vascular biology” In this study, finasteride significantly reduced plasma cholesterol and triglycerides and decreased atherosclerotic lesion burden in mice, suggesting its potential role in delaying cardiovascular disease.
1 citations
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January 2019 in “Przegla̧d dermatologiczny” This article reviews the concept of cardiodermatology and its application in clinical practice but does not present new empirical findings.