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Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Skin-derived precursors in hair follicles come from different origins but function similarly.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Turing patterns are now recognized as important in developmental biology.

Lower SHBG levels may increase the risk of PCOS.

Wool follicles are complex, involving interactions between different cell types and structures.

BMP2 and BMP7 have opposite roles in feather formation.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Sponge helps heal wounds faster with less inflammation and better skin/hair growth.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.