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BMP2 and BMP7 have opposite roles in feather formation.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Understanding skin structure and development helps diagnose and treat skin disorders.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.

Some people with chronic hair loss may have thyroid autoimmunity.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Antibody treatments show promise for hair loss but need more research.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

Certain circular RNAs are crucial for wool growth and curvature in goats.

Notch signalling helps skin cells differentiate and prevents tumors.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Most cutaneous adnexal tumors examined were benign and resembled common skin tumors.

ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.

Curved hair can develop when hair cells merge abnormally during growth.

A woman's progressive hair loss was correctly diagnosed as a rare condition called fibrosing alopecia in a pattern distribution after initially being mistaken for a more common type.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Cathepsin L is essential for normal hair growth and development.

Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Minoxidil can reduce functions related to androgen receptors.

EGFR helps control how hair grows and forms without needing p53 protein.