September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that TGM2 appears to play a crucial role in sebocyte differentiation and may act as a negative regulator of lipid metabolism in sebaceous glands.
4 citations
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September 2024 in “BMC Cancer” In this prospective phase II clinical trial, researchers are investigating whether adding dutasteride to combined androgen blockade can improve the response rate and clinical outcomes for patients with androgen receptor-positive recurrent or metastatic salivary duct carcinoma.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study revealed that tofacitinib may inhibit CD8+ T cell infiltration in alopecia areata by modulating the linoleic acid metabolism-Mg2+ pathway, providing new insights for potential treatments and diagnosis.
January 2014 in “韓方眼耳鼻咽喉皮膚科學會誌 = The journal of Korean Medicine Ophthalmology & Otolaryngology & Dermatology” This study found that pharmacopuncture and needle-embedding therapy may improve hair loss and physical condition in women with androgenetic alopecia, though further clinical research is needed.
December 2022 in “Biochemical and Biophysical Research Communications” This study found that HtrA2 inactivation in mnd2 mice is associated with delayed hair cycle phases and growth retardation of adipocytes, suggesting HtrA2's role in regulating adipogenesis-related hair growth.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study used machine learning to identify molecular predictors of drug response in alopecia areata, suggesting a tool for predicting treatment efficacy based on gene signatures.
1 citations
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January 2000 in “Journal of pharmacopuncture” This study confirmed that microneedle therapy systems (MTS) significantly improve hair growth and skin conditions, including acne and acne scars, without serious side effects.
November 2019 in “Harper's Textbook of Pediatric Dermatology” This article reviews Netherton syndrome, focusing on its genetic basis, clinical presentation, and treatment options, and reports no clinical results; the authors mention potential benefits of targeted therapies and gene therapy.
1 citations
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January 2013 July 2024 in “Journal of Investigative Dermatology” This study found that systemic treatment with DS77754007, a KLK5 inhibitor, improved skin symptoms in a mouse model of Netherton Syndrome more effectively than certain antibody treatments, suggesting KLK5 inhibition as a promising therapeutic approach for this condition.
This study found that 62 plasma proteins are significantly associated with the risk of obstructive sleep apnea, offering potential targets for new therapeutic strategies.
9 citations
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November 2019 in “Cell calcium” This study found that a mutation causing Stormorken syndrome in mice led to skeletal abnormalities and unusual hair growth, showcasing the STIM1 R304W protein’s role in bone development and cell fate.
12 citations
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February 2023 in “Applied and Environmental Microbiology” This study reported that structure-guided engineering of CYP154C2 mutants significantly improved the 2α-hydroxylation of androstenedione and testosterone, with enhanced conversion efficiency and substrate selectivity compared to the wild-type enzyme.
August 2023 in “Zenodo (CERN European Organization for Nuclear Research)”
44 citations
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November 2016 in “Journal of The American Academy of Dermatology” This article updates a diagnostic tool (SALT II) for assessing hair loss by adding more precise measurements of scalp surface area, particularly useful for various types of alopecia.
January 2020 in “대한피부과학회지” This study found that oral dutasteride increased hair density but not thickness in female-pattern hair loss patients, suggesting a potential mechanism involving β-catenin activity.
39 citations
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March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that GLI2 plays a key role in activating follistatin, an activin/BMP antagonist, in response to hedgehog signaling in human epidermal cells, with implications for hair follicle development and basal cell carcinoma.
25 citations
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April 2017 in “PloS one” In this study, specific SNPs in the FST gene were significantly associated with various wool quality traits in Chinese Merino sheep, suggesting potential markers for breeding programs.
September 2023 in “Zenodo (CERN European Organization for Nuclear Research)” April 2020 in “Journal of the Endocrine Society” In this case study, the use of somatostatin analogues was effective in localizing and confirming a neuroendocrine lung tumor as the source of ectopic ACTH syndrome, leading to marked clinical improvement in a patient unable to undergo surgery.
46 citations
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May 2021 in “Stem Cell Research & Therapy” This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.
14 citations
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November 2024 in “Pharmaceuticals” This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.
1 citations
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January 2017 in “SAGE Open Medical Case Reports” This case report suggests that exacerbations of alopecia areata in a 40-year-old woman may be associated with sodium tetradecyl sulphate foam sclerotherapy treatments for varicose veins.
3 citations
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June 2002 in “PubMed” This case report describes the diagnosis of Netherton's syndrome in two young sisters, attributing their serious erythrodermia, poor hair growth, and atopic conditions to this hereditary condition.
August 2025 in “International Journal of Molecular Sciences” This study found that arginine vasotocin is evolutionarily conserved across diverse taxa and may play roles in neuroendocrine, immune, and stress signaling, with potential antimicrobial applications.
26 citations
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December 2009 in “Laser Physics” This study observed that caffeine-containing shampoo can penetrate hair follicles to a depth of approximately 200 μm and remains detectable even after 24 hours, suggesting a potential long-term reservoir effect.
25 citations
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December 2008 in “Journal of Dermatological Case Reports” In this study, R-CSLM showed promise in evaluating hair shaft diseases by providing high-quality images of hair structures, although further development is necessary for follicle and perifollicular area analysis.
24 citations
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March 2016 in “Journal of Investigative Dermatology” This study suggests that TIP39 and its receptor PTH2R, identified in human epidermis, may play a role in keratinocyte function and influence skin differentiation.
21 citations
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October 2023 in “The Journal of Physical Chemistry C” This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.
20 citations
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February 2023 in “Biology” This review highlights the possibility of safely altering hair color through innovative cosmetics by targeting key biological processes in hair follicles, using insights from mammalian pigmentation studies and drug-induced hair color changes as potential pathways.