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This study found that the optimized AR antagonist compound 39 showed potent hair growth activity with improved safety in mice, suggesting potential for better topical treatments for androgenetic alopecia.

In a mouse hair-growth model, this study found that the optimized compound 39 matched the efficacy of pyrilutamide for androgenic alopecia, with faster response and maintained safety, suggesting it as a promising topical AR antagonist with reduced systemic toxicity risk.

This study found that Danthron induced apoptosis in a human malignant melanoma cell line through mitochondrial, endoplasmic reticulum, and death receptor pathways.

This study describes how the argan oil industry in southwestern Morocco, originally controlled by Amazigh women, has shifted to being largely dominated by the state and businessmen, with the majority of women now only involved in traditional nut cracking, despite mechanization of other production steps.

This study found that in male yaks, 5α-red1 may play a crucial role in synthesizing DHT to promote hair follicle growth, while E2 synthesized by epithelial cells may inhibit this growth through ERα.

In this study, researchers found that AGD1 is crucial for membrane recruitment during root hair development in Arabidopsis thaliana, with its pleckstrin homology domain essential for targeting specific plasma membrane regions.

This study developed dissolving microneedles incorporating a new AR degrader for treating androgenetic alopecia, showing that a single application leads to superior hair regeneration compared to daily minoxidil, without systemic toxicity or androgen-related issues.

This study reports a notable case of a patient with psoriatic arthritis and alopecia universalis who experienced significant improvement in both conditions after treatment with the JAK1 selective inhibitor upadacitinib, suggesting its potential efficacy for alopecia universalis, especially in cases involving inflammatory arthritis.

This study used developing mouse hair follicles to explore early epithelial bud formation, finding that the Rho GTPase regulator ARHGEF3 plays a crucial role in regulating cell fate and cadherin patterning, with knockouts showing disrupted morphology and increased straight hair follicle growth.

Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.

This review explores the potential of Arabian Bidara leaves as a hair growth enhancer based on its shared chemical compounds with other known hair-fertility-promoting plants, but it reports no new experimental results.

This study found that Agaricus bisporus-derived β-Glucan particles showed potential as an anticancer, antimicrobial, and antioxidant agent, inducing apoptosis and disrupting mitochondrial membrane potential in cervical cancer HeLa cells.

This study found that variations in the androgen receptor gene influenced memory function in women, with GGN repeat polymorphisms significantly affecting logical memory performance only in females.

In this study, Swedish men carrying the AR haplotype H2 were found to have a significantly lower risk of prostate cancer compared to those with the more common H1 variant.

In this study, researchers developed "Akaro Spectra," an antiparasitic tablet for dogs using cryodestruction of plant materials, which showed 100% efficacy against Otodectes cynotis ticks by the second day and 93.76% efficacy against Ixodes, Dermacentor, and Rhipicephalus ticks.

This review discusses the role of the androgen receptor in breast cancer diagnosis and treatment, and notes a lack of new research results on its therapeutic potential.

Haplogroup X found in Altaian population supports Amerindian origin.

This article reports increased DNA methylation of the androgen receptor gene in the occipital hair follicles of men with androgenetic alopecia but presents no clinical results.

This article describes a personal movie from 1969 documenting skull trephination surgery by Gusii tribal surgeons in Kenya, without presenting new clinical results.

This study found that specific genetic markers near the androgen receptor gene are significantly more common in men with male pattern baldness, suggesting a genetic component in its development.

Abrus precatorius has medicinal benefits but can be toxic.

This study reports that different animal species exhibit distinct hair scale patterns and elemental compositions, which can aid forensic investigations in identifying animal hair.

In this study, candidate compound 39 demonstrated potent androgen receptor antagonism and faster hair-growth efficacy in a mouse model compared to pyrilutamide, while maintaining favorable safety and pharmacokinetic profiles, suggesting potential for topical use in androgenic alopecia.

This case report highlights a rare presentation of APS-1 in a 28-year-old Pakistani male with cardiovascular and pulmonary symptoms, illustrating the importance of early recognition and multidisciplinary management for improved patient outcomes.

This study synthesized nonsteroidal ligands as second-generation androgen receptor agonists and identified three compounds with significant anabolic activity and moderate to minimal androgenic activity in vivo.

In this study, researchers developed a new topical atraric acid formulation, AA-TF#15, which showed a significantly higher drug penetration and increased hair regrowth in mice compared to minoxidil and finasteride treatments, suggesting its potential effectiveness for treating scalp androgenic alopecia.

This study identified novel selective androgen receptor modulators with enhanced in vivo pharmacological activity through structure-activity relationship analysis in castrated rats.

This review discusses the wide range of physiologic skin changes during pregnancy and highlights less frequently recognized changes, based on literature from the past decade, without reporting new clinical results.

This study identifies the PI4P-RHD4 module as a key regulator of GET pathway receptor dynamics in Arabidopsis, affecting TA protein insertion and root hair growth.