April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting the Mitochondrial Pyruvate Carrier in human hair follicles ex vivo activated the integrated stress response, affecting cell proliferation and metabolism.
24 citations
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July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.
September 2023 in “Journal of the American Academy of Dermatology” Recognizing IPPP is crucial to prevent misdiagnosis and unnecessary treatments.
72 citations
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January 2003 in “American Journal of Pathology” This study found that the co-activator CBP enhances the agonistic action of hydroxyflutamide on androgen receptors, suggesting a mechanism for therapy resistance in prostate cancer.
3 citations
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April 2024 in “JAAD Case Reports” This article reviews DPCP's use as a topical immunotherapy for alopecia areata and discusses its suggested mechanism, but reports no clinical results.
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
February 2024 in “Cancers” This review highlights recent progress in developing androgen receptor degraders, such as PROTACs, for treating castration-resistant prostate cancer, and notes that several have entered phase I or II clinical trials, showcasing potential to address drug resistance challenges.
August 2024 in “Scientia Horticulturae” In this study, researchers observed that inoculation with Funneliformis mosseae significantly enhanced growth, biomass, and root architecture in trifoliate orange plants, with variations in auxin levels and gene expression, suggesting PtPIN6 as a key gene involved in root hair development regulation.
184 citations
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September 2006 in “PLoS Genetics” This study found that loss of Apc due to K14-cre-mediated gene recombination in mice led to aberrant growth in ectodermally derived squamous epithelia, implicating its critical role in specifying epithelial cell fates during embryonic development.
May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.
7 citations
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December 2021 in “European Respiratory Review” This review covers the current status of the interstitial pneumonia with autoimmune features (IPAF) category, pointing out the need for revision of its criteria to establish it as a standalone diagnostic term, but reports no new clinical findings.
11 citations
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January 2021 in “British Journal of Dermatology” This report describes a new case of syndromic ichthyosis caused by compound heterozygous mutations in AP1B1, detailing the associated clinical features and molecular consequences in the patient.
1 citations
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October 2025 in “Micromachines” This review highlights the potential of integrating point-of-care testing with allele-specific amplification techniques like AS-PCR, AS-LAMP, and AS-RPA to improve the efficiency, accuracy, and affordability of genotyping single nucleotide polymorphisms associated with human diseases.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that CD200R expression is significantly reduced in an experimental mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.
3 citations
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June 2022 in “European journal of human genetics” This study reports the first cases of recessive KRT17-related pachyonychia congenita involving all ectodermal derivatives in seven members of two consanguineous Pakistani families.
This review examines complex regional pain syndrome (CRPS I) mechanisms, including immune dysregulation and psychological factors, but reports no new clinical results; the authors highlight potential diagnostic refinements.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
3 citations
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April 2024 in “Molecular Human Reproduction” This study found that paxillin knockdown in human granulosa-derived cells and mouse models decreased androgen receptor protein levels and altered gene expression, suggesting paxillin's role in protecting against androgen excess effects, as observed in a polycystic ovary syndrome mouse model.
November 2023 in “Frontiers in pharmacology” This review highlights the ongoing need for novel treatments for autosomal recessive congenital ichthyoses, suggesting that drug repositioning, utilizing existing medications or biologics, could provide more affordable and effective options for managing this lifelong skin condition.
6 citations
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June 2011 in “British Journal of Dermatology” This study found that individuals with alopecia areata had significantly higher serum levels of retinol-binding protein 4 and increased IgG immunoreactivity against it, suggesting a role in the disease's pathogenesis.
11 citations
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March 2006 in “Journal of medical ethics” This report describes a case of twins with alopecia areata totalis who did not respond to corticosteroids but showed significant hair growth with platelet rich plasma injections, suggesting PRP's potential as an alternative treatment.
June 2022 in “Plastic & Reconstructive Surgery Global Open” This document reviews various studies presented at the Plastic Surgery Research Council (PSRC) Annual Meetings and reports no new research findings; it discusses topics ranging from reconstructive techniques to gender-affirming surgeries.
This study developed and tested continuous implanters for dermal papilla cell aggregates, finding that the bar-cartridge type implanter is the most effective design for continuous cell implantation in androgenetic alopecia research.
November 2022 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” In this study, the pi4kβ1β2 double mutant in Arabidopsis thaliana exhibited altered root growth, increased susceptibility to Blumeria graminis, and a potential correlation between PI4K activity and auxin response and immunity due to changes in vesicular trafficking and actin filaments.
July 2026 in “Preprints.org” This review outlines the optimization of platelet concentrates for hair loss treatment and suggests extracellular vesicles as a key future element, aiming to advance point-of-care regenerative therapies despite the need for a unified framework and further research on underlying mechanisms.
1 citations
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May 2018 in “Plastic and reconstructive surgery. Global open” This article describes the 2017 ISPRES World Congress in Dubai, highlighting its focus on fat grafting and regenerative surgery, and reports no new research results; future collaboration with ASPS is anticipated.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, Mononuclear Cells provided site-specific protection against chemotherapy-induced alopecia in rats treated with Ara-C, but not with CTX or VP-16, while PRP showed no protective effect.
January 2021 in “Deep Blue (University of Michigan)” This study found that LepRb neurons in the brain are important targets for androgen action and influence sex-specific differences in reproductive and metabolic regulation, implicating them in conditions such as polycystic ovary syndrome.
July 2024 in “Periodontology 2000” This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.
4 citations
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February 2022 in “International Journal of Dermatology” This study observed that porocarcinoma exhibited a relatively low rate of local recurrence, nodal metastases, and mortality over a follow-up period exceeding five years.