43 citations
,
February 2008 in “Journal of cutaneous pathology” This study revealed that during fetal development, MITF and Mart-1 expressing melanocytes progress from the dermis to the epidermis and hair follicles, with MITF possibly marking follicular stem cells.
6 citations
,
September 2007 in “PubMed” This review explores the role and formation of stem cell niches and how they regulate stem cell self-renewal and proliferation, but it reports no new experimental results.
4 citations
,
January 2014 in “Vegetos” This review discusses various medicinal properties and traditional uses of Ziziphus species in human health, emphasizing their potential for new therapeutic applications but reports no new clinical results.
3 citations
,
July 1997 in “Current problems in dermatology” This article reviews 25 years of hair restoration advancements, highlighting the shift towards techniques that emphasize naturalness and undetectability, and reports no new research findings.
This hypothesis paper suggests that sexual and cognitive dysfunctions reported by some men after using finasteride and dutasteride may stem from vascular and tissue changes in penile tissue triggering broader inflammatory effects.
This letter humorously reflects on aging and disputes the notion of "Geezer syndrome" linked to the Great Depression, emphasizing resilience and growth in knowledge over time.
August 2024 in “EMJ Dermatology” This review addresses the causes, mechanisms, and treatment options for the most common non-scarring alopecias in females, including telogen effluvium, alopecia areata, and female pattern hair loss.
May 2026 in “Jurnal Pendidikan Kimia Fisika dan Biologi” This study found that rebonding hair straightening treatments visibly damage the hair cuticle, causing surface erosion and cracks, as shown through Scanning Electron Microscopy analysis.
July 2025 in “International Journal of Health and Medicine” In this study, dual therapy with tamsulosin and solifenacin significantly improved urinary symptom severity and bladder capacity in BPH patients, but did not alter post-void residual urine volume. This supports using the combination therapy for managing LUTS, especially for storage-related symptoms, in clinical settings.
This study found that pregnant women experiencing hair loss in the first and second trimesters had significantly lower levels of vitamin D3 and ferritin compared to those not experiencing hair loss, with these levels explained by typical pregnancy physiology.
2 citations
,
April 2023 in “PubMed” In this study, researchers in Basrah, Iraq, observed that iodine deficiency in cross-breed goat kids led to goiter, slow growth, and various biochemical changes, including increased TSH and hypercholesterolemia, suggesting the need for improved maternal diet to reduce these issues and associated mortality risks.
This chapter reviews the clinical and morphological diagnostic features of various hair dysplasias, including atypical pili torti, pseudomonilethrix, and trichothiodystrophy, and reports no new results.
949 citations
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January 2001 in “Cell” This study demonstrated that multipotent stem cells in adult mice whisker follicles migrate to produce whisker growth, and that this process requires precise control of stem cell trafficking.
638 citations
,
October 1997 in “Nature”
408 citations
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January 2017 in “Science” This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.
322 citations
,
January 1997 in “Thrombosis and Haemostasis” This review discusses factors influencing angiogenesis, focusing on vascular permeability factor as a key inducer and thrombospondin as a notable inhibitor, and recommends exploring molecular mechanisms for therapeutic interventions.
221 citations
,
January 2014 in “Human Reproduction” This study found that the prevalence of polycystic ovary syndrome was 16.6% with Rotterdam criteria but decreased to 6.3% or 8.5% when using alternative criteria involving antral follicle count or anti-Müllerian hormone.
205 citations
,
August 2007 in “Experimental Cell Research” This review discusses advances in understanding mammalian stem cell niches, particularly in bone marrow, tooth, and hair follicle, and highlights the potential for developing therapies targeting these niches for tissue repair.
190 citations
,
July 2006 in “Experimental Dermatology” This review discusses the role of the sonic hedgehog pathway in skin development and cancer, highlighting its potential as a target for chemoprevention and treatment; it reports no new findings.
114 citations
,
February 2012 in “International Journal of Dermatology” This review examines the dermatologic effects of tobacco use and nicotine, noting potential benefits and drawbacks for various skin conditions, but reports no new clinical results.
113 citations
,
July 2020 in “International Journal of Molecular Sciences” This review suggests that allogenic adipose stem cell and extracellular matrix transplants may be safe and effective for various medical conditions, based on available studies.
106 citations
,
March 2013 in “Nature Communications” This study found several microRNA-related genetic variants linked to epithelial ovarian cancer risk, with a notable association at the 17q21.31 region, suggesting potential new susceptibility genes.
98 citations
,
July 1983 in “Journal of Steroid Biochemistry” This study in the Arab population of Gaza described pseudohermaphroditism due to 17β-HSD deficiency, where individuals showed marked masculinization after puberty despite inadequate androgen proportions.
97 citations
,
March 2006 in “Journal of Investigative Dermatology” This study identified four novel DSG4 mutations associated with monilethrix in 12 Jewish families, suggesting a recessive inheritance pattern and broader prevalence of DSG4-related hair disorders than previously recognized.
84 citations
,
February 2015 in “Experimental Dermatology” This review discusses the role of PPARs in skin health, suggesting both potential benefits and adverse effects, but reports no new experimental results; the authors emphasize the need for more research to understand these pathways.
84 citations
,
August 2013 in “Journal of Cellular Biochemistry” This study found that stem cells from the human umbilical cord's Wharton's jelly may significantly enhance healing in excisional and diabetic wounds compared to controls.
82 citations
,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
74 citations
,
January 2013 in “Journal of Investigative Dermatology” Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
71 citations
,
May 2024 in “New England Journal of Medicine” This study investigated the impact of the JAK inhibitor ruxolitinib on APS-1 patients, reporting that treatment decreased excessive T-cell-derived interferon-γ, normalized inflammatory markers, and led to remission of several autoimmune symptoms without serious adverse effects.
68 citations
,
January 2022 in “International Journal of Molecular Sciences” This review summarizes factors involved in polycystic ovary syndrome pathogenesis and management, highlights commonly prescribed and repurposed medications, and calls for well-designed clinical trials to evaluate these treatments further.