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Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

The article concludes that creating a detailed map of normal human skin at the single-cell level is important.

The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Borneol Essential Oil could be a natural and safe acne treatment.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.

Finasteride reduces prostate size and PSA levels in young patients.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

A postmenopausal woman's facial redness, acne, and excess hair were caused by too much hormone therapy for insomnia, but improved after stopping the treatment.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.