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Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Whale genes show changes that help them live in water, like less hair and better flippers.

Netherton syndrome can cause severe dehydration, infections, and growth issues in infants.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

Blocking testosterone speeds up wound healing in males.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Genes and hormones cause hair loss, with four genes contributing equally.

Blocking testosterone speeds up wound healing in males.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Scalp melanoma, a deadly skin cancer, is often found late due to its hard-to-see location, especially in older men. Early detection, possible treatments, and the role of hairdressers in spotting it early are discussed. More research is needed to improve detection and treatment.

Moxibustion may help improve ovarian function by changing androgen levels.

A substance called Cell-free fat extract can effectively treat common hair loss by increasing hair growth and density.

Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.

Two siblings with a rare type of rickets and hair loss had low vitamin D levels, which is not typical for their condition.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Ozone therapy might improve cancer treatment and reduce its side effects.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.