Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the multifactorial origins and pathophysiology of PCOS and highlights the effectiveness of lifestyle modifications as a first-line intervention, reporting no new research results.

This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.

This review highlights the increasing clinical applications of high-frequency ultrasonography in dermatology, particularly for assessing the depth of skin tumors and monitoring inflammatory skin diseases, but reports no new clinical results.

This study found that myo-inositol treatment reduced hirsutism and acne in women with PCOS by improving their metabolic profiles, including lower insulin and testosterone levels.

This review examines testosterone's role in male health and aging but reports no new clinical results; the authors highlight the need for further research on optimal testosterone levels to prevent age-related conditions.

This article discusses the role of dihydrotestosterone in human prostatic adenocarcinoma growth and suggests that 6-methyleneprogesterone could be used to inhibit DHT for treating hormone-responsive prostate cancer, without new clinical findings.

This study found that the antiandrogen drug enzalutamide reduced TMPRSS2 levels and significantly decreased SARS-CoV-2 entry and infection in lung cells, supporting further clinical trials for COVID-19 treatment.

This study found no evidence of androgen deficiency or decreased peripheral androgen action in men with persistent sexual symptoms after finasteride use, but identified links to depressed mood and abnormal brain function.

This review discusses the various roles of RANK signaling in bone remodeling, immune function, and epithelial differentiation, highlighting its potential involvement in cancer mechanisms; it reports no new clinical results.

This review discusses the role of CYP gene polymorphisms in exacerbating hyperandrogenism in women with PCOS and reports no clinical results; further validation of this hypothesis is needed.

This review discusses the presence of the StAR protein in 17 non-classical steroidogenic tissues, suggesting that advanced detection methods are needed for a complete understanding of its functions in these tissues.

This review discusses the roles and mechanisms of Wnt signaling in embryonic and adult stem cells and its association with cancers, and reports no new experimental findings.

In this review, researchers explored the roles of vitamins A, B3, C, D, and E in skin immunity, highlighting their potential as therapeutics for skin diseases due to their antioxidant, anti-inflammatory, and antimicrobial properties.

This study found that DKK1 and WNT10b are paracrine factors that modulate hair follicle stem cell differentiation inhibition, contributing to androgenetic alopecia by affecting Wnt signaling in androgen-sensitive dermal papilla cells after dihydrotestosterone stimulation.

This review explores the role of Eph receptors and ephrins in skin cell processes, discussing their potential for therapeutic targeting in dermatological disorders, but it presents no new research findings.

This study found that isotretinoin, a drug commonly used for acne, inhibits polyamine transport in Trypanosoma cruzi, leading to trypanocidal effects, and suggests its potential as a treatment for Chagas disease without affecting mammalian cell viability.

This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.

This article discusses the role of growth hormone, insulin, and IGF-1 in acne development and highlights how diet and syndromic evidence support their involvement, but presents no new clinical findings.

In this study, Geranium sibiricum L. extract promoted hair growth in vitro with human dermal papilla cells and in vivo in mice, outperforming minoxidil by proliferating cells and stimulating growth factor expression, suggesting its potential as a hair growth treatment.

This abstract discusses the uncertain role of the vascular system in hair loss and highlights the unexplained aspects of various types of alopecias; it reports no new research findings.

In this study, DHT was found to inhibit hair growth in mice by decreasing IGF-I production in dermal papillae through reduced sensory neuron stimulation.

This review discusses the complexity of neuroactive steroid therapies for neuroprotection and reports no new clinical findings, suggesting potential unexpected effects in the brain compared to systemic levels.

This study used bioinformatics to explore molecular differences in testicular and ovarian responses to SARS-CoV-2, identifying genes that could be associated with sex differences in infection outcomes.

This study identified overexpression of certain immune-related genes and underexpression of genes in specific signaling pathways in premature androgenetic alopecia, suggesting potential new therapeutic targets.

This study suggests that hormonal changes may contribute to the persistent symptoms of long COVID, with specific patterns observed in serum hormone levels related to fatigue and sensory dysfunction.

This review examines hormonal influences on acne development and available hormonal therapies but reports no new clinical results.

This review highlights the light microscopic features of various infectious and non-infectious hair conditions and reports no new clinical results.

This review examines the benefits and potential risks of androgen replacement therapy for male hypogonadism but reports no new clinical results; the authors highlight the need for careful risk assessment, especially in older men.

This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.

This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.