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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.