12 citations
,
July 2023 in “Journal of the European Academy of Dermatology and Venereology” Upadacitinib improved Crohn's disease, atopic dermatitis, and alopecia areata in one patient.
26 citations
,
October 2016 in “Biomolecules & Therapeutics” This study found that 3-Deoxysappanchalcone may stimulate hair growth in mice by promoting proliferation of hair follicle dermal papilla cells through WNT/β-catenin and STAT signaling modulation.
323 citations
,
November 1984 in “Journal of Investigative Dermatology” 8 citations
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March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
118 citations
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January 1992 in “Experientia” 28 citations
,
September 2013 in “Biogerontology” 135 citations
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March 2000 in “Journal of Biological Chemistry” This review discusses the roles of the Agouti and Agouti-related proteins in pigmentation and energy regulation and reports no new experimental findings.
4 citations
,
September 2020 in “Cell division” In this study, XMU-MP-1 unexpectedly reduced cell proliferation and altered cell cycle progression in a model human hair follicle, possibly due to off-target kinase inhibition.
37 citations
,
April 2015 in “Development Growth & Differentiation” This article introduces the concept of organ size control in regeneration, regulated by the Hippo signaling pathway, but reports no new experimental results.
3 citations
,
August 2013 in “Journal of the American Academy of Dermatology” This study identified a novel microscopic "arrow sign" in hair root sheaths of patients on EGFR inhibitors, potentially aiding in diagnosing related hair changes and differentiating from fungal infections.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study tested a microneedle patch on rabbit and pig models to support skin regeneration, revealing that the treatment accelerated wound closure, reduced scar formation, and promoted hair-bearing tissue and follicle growth, suggesting a trauma-guided framework for skin restoration.
17 citations
,
May 2019 in “Journal of International Medical Research” In this study, the use of Xiaoaiping alongside routine chemotherapy improved side effects such as alopecia, nausea and vomiting, diarrhea, and enhanced quality of life in breast cancer patients compared to chemotherapy alone.
150 citations
,
May 1993 in “The journal of cell biology/The Journal of cell biology” This study suggests that mNotch expression plays a significant role in hair follicle differentiation and cell fate selection within the follicle during development.
July 2005 in “Journal of The American Academy of Dermatology” This article discusses the various uses of the cotton-tipped applicator in dermatologic surgery, highlighting its innovative role as a suture scissors stabilizer, but reports no clinical results.
This narrative review examined the potential of hibiscus leaves and apple skin as natural ingredients for hair tonics and reported their effectiveness in addressing hair loss, highlighting properties like strong antioxidant content and ability to strengthen hair roots.
May 2026 in “Theranostics” This study found that the DKK3-CKAP4 signaling axis is involved in fibroimmune remodeling in androgenetic alopecia and that targeting this pathway may restore a regenerative hair follicle environment, offering a potential therapeutic strategy to counteract hair follicle miniaturization.
February 2026 in “Indian Journal of Dermatology” This case report found that a 48-year-old woman with idiopathic twenty-nail dystrophy experienced significant improvement in nail appearance after six months of treatment with oral Upadacitinib.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study found that the novel IPC analog SIG-1451 may inhibit inflammatory cytokine release in cell-based assays relevant to allergic dermatitis.
August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal” This study found that callus extracts from apple 'Hirosaki' may improve collagen synthesis, hair follicle cell proliferation, and possess significant anti-inflammatory properties.
12 citations
,
December 2021 in “Aging” This study demonstrated that a new non-invasive method for collecting and analyzing mouse hair follicles could replace traditional biopsy methods, providing advantages for translational research and routine applications.
24 citations
,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers identified two new keratin-associated proteins, hKAP1.6 and hKAP1.7, in human hair follicles, contributing to understanding hair fiber differentiation.
April 2025 in “Journal of Diabetes & Metabolic Disorders” This study found that linc-PINT expression was significantly decreased in patients with atrial fibrillation compared to healthy controls, while several TGF-β signaling genes were increased, suggesting a potential role in heart arrhythmias' pathogenesis.
10 citations
,
January 2019 in “Advances in Clinical and Experimental Medicine” This meta-analysis reported a significant association between vitamin D receptor gene ApaI polymorphism and polycystic ovary syndrome risk, with variations observed between Asian and Caucasian populations.
16 citations
,
April 2018 in “Animal Genetics” This study identified two significant genomic regions potentially involved in hair development and growth in Casertana pigs, highlighting FOXN3 and ARHGEF10 as candidate genes associated with a hairless phenotype.
1 citations
,
September 2024 in “Animals” In this study, researchers identified six unique genetic variants of a sheep gene, KRTAP19-3, with specific variants linked to changes in wool fibre traits, such as increased fibre diameter variability, suggesting these genetic differences affect wool characteristics in Chinese Tan sheep.
April 2019 in “Journal of Investigative Dermatology”
This study analyzed the genetic variations of the KAP20-1 gene in Chinese Tan sheep lambs and found that the G variant was linked to an increased mean fibre curvature in their fine wool fibres, potentially influencing breeding strategies for this wool trait.
January 2018 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Scalp micropigmentation is a process where tiny dots of pigment are tattooed onto the scalp to create the appearance of a shaved head or fuller hair.
47 citations
,
September 2004 in “Journal of Biological Chemistry” This study provides evidence supporting a regulatory relationship between the transcriptional regulator Hoxc13 and Krtap16 genes, which are crucial for proper hair growth in mice.
4 citations
,
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed the iCOUNT tool, which provides insights into stem cell behavior by tracking cell division events and molecular consequences in human and mouse neural stem/progenitor cells.