January 2024 in “Biomedicines” This review discussed the cutaneous manifestations of APECED, highlighting chronic mucocutaneous candidiasis, alopecia areata, and vitiligo, while emphasizing the importance of early detection and monitoring for accurate diagnosis and patient care in various populations.
May 2015 in “Journal of The American Academy of Dermatology” Both treatments help with hair regrowth in alopecia areata, but azathioprine has milder side effects than betamethasone.
January 1983 in “Elsevier eBooks” This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.
January 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that AP-2α and AP-2β are critical for maintaining epidermal homeostasis in adult skin, with their combined loss leading to severe skin and hair abnormalities and early skin inflammation due to impaired keratinocyte differentiation.
June 2025 in “International Medical Case Reports Journal” This case study reported on a 30-year-old male with autoimmune polyglandular syndrome type 2, highlighting rare co-occurrence with alopecia universalis and emphasizing the importance of recognizing non-endocrine symptoms for early diagnosis and management of autoimmune endocrinopathies.
June 2025 in “Molecular Therapy — Nucleic Acids” In this study, researchers identified a specific DNA aptamer, Ap.OR2AT4.17, that effectively prolonged hair growth and increased hair shaft elongation in organ-cultured human hair follicles by targeting the olfactory receptor OR2AT4. This finding suggests the aptamer's potential as a novel therapy for hair loss disorders.
6 citations
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November 2016 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This survey found support among BAAPS members for using procedure-specific consent forms to improve clarity and consistency in patient information for aesthetic procedures.
This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.
January 2026 in “Journal of Cosmetic Dermatology” In this 10-patient exploratory study, the researchers found that topical application of 4-aminopyridine 5% combined with microneedling did not improve hair density or quality in men with androgenetic alopecia, suggesting limited efficacy in this context despite promising results in animal wound models.
22 citations
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November 2002 in “Clinical journal of oncology nursing” This article discusses arsenic trioxide as a treatment for refractory or relapsed acute promyelocytic leukemia, noting its effectiveness and manageable side effects.
This study found that a short-term treatment with all-trans retinoic acid may effectively stabilize platelet counts in idiopathic thrombocytopenic purpura patients experiencing fluctuations during thrombopoietin receptor agonist therapy.
April 2012 in “Informa Healthcare eBooks” Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.
July 2024 in “New Phytologist” This study suggests that the transcription factor PDF2 in Arabidopsis may link lipid sensing with growth responses to phosphate starvation by acting as a sensor for lyso-PCs through its START domain.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that YAP1 localization and expression patterns in human skin xenografts resembled pathological conditions, suggesting that YAP1 may be a potential target for treating skin pathologies.
In an outpatient cardiology center, this study found that introducing the AHA/ACC ABI screening protocol significantly increased the frequency of ABI ordering by 31.6% for symptomatic patients.
36 citations
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July 2017 in “Journal of controlled release” In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.
December 2025 in “Clinical Cosmetic and Investigational Dermatology” In this report, a unique female presentation of IFAP syndrome is described, featuring musculoskeletal contractures but no photophobia, highlighting the importance of early detection and multidisciplinary care to improve outcomes and prevent disability.
2 citations
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January 2025 in “动物学研究” In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.
May 1981 in “Inpharma (Balgowlah)” Medroxyprogesterone acetate improved sleep apnea symptoms in some obese patients.
June 2024 in “Indian Journal of Veterinary Medicine” This case report describes a Salem black kid with alopecia and other symptoms, which was diagnosed with anaplasmosis due to Anaplasma ovis infection combined with copper deficiency, as confirmed by laboratory tests including blood smears and serum biochemistry.
May 2011 in “Value in Health” This review assessed patient-reported outcome measures for alopecia treatments but found that none met current FDA guidelines; however, some could potentially be adapted for more comprehensive use.
September 2023 in “Journal of the American Academy of Dermatology” In this study of pediatric melanocytic lesions, researchers at Massachusetts General Hospital observed no concurrent BAP1 loss and BRAFV600E positivity, characteristics of adult BIMT, suggesting that these tumors may develop at a later age rather than in childhood.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that AP-2α and AP-2β transcription factors are crucial for maintaining adult skin homeostasis, with their inactivation in keratinocytes leading to impaired differentiation, hair abnormalities, and inflammation, highlighting their key regulatory roles.
3 citations
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May 2021 in “PloS one” This study found that Jordanian males use oral contraceptive pills, particularly for bodybuilding, based on recommendations from gym coaches, highlighting unexpected uses of these medications.
1 citations
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July 2016 in “Nottingham ePrints (University of Nottingham)” This study developed mathematical models to simulate phosphate uptake in rice and Arabidopsis, suggesting a phosphate-sensitive repressor could regulate PHO2 mRNA levels, and highlighting potential targets and traits for improving phosphorus-use efficiency.
October 2025 in “Open Repository of the University of Porto (University of Porto)” Dutasteride is more effective than finasteride for hair growth, and sublingual apomorphine quickly improves Parkinson's symptoms.
This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.
June 1985 in “Journal of the American Academy of Dermatology”
April 2023 in “Journal of Investigative Dermatology” In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
December 2013 in “International Journal of Dermatology” The clinical signs of Adams-Oliver syndrome can vary greatly, even among family members.