September 2002 in “Dermatologic Surgery” This study found that the prevalence of male pattern baldness in the Asian population in Bangkok is higher than previously thought, approaching rates seen in Caucasians.
2 citations
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March 2025 in “JAMA Dermatology” This review evaluates the quality of alopecia areata-specific patient-reported outcome measures and suggests that more high-quality validation studies are needed to enhance their reliability and validity.
This review reports that extracts from the plant Eclipta alba, traditionally used in herbal medicine, may promote hair growth by inhibiting TGF-β1 expression and functioning as a 5α-reductase inhibitor, potentially benefiting androgenic alopecia treatment.
January 2023 in “Social Science Research Network” This case study describes the treatment of a 27-year-old Filipino male with acute patchy hair loss due to alopecia areata, emphasizing the disease's unpredictable progression.
This article reviews differences in hair characteristics between Asians and Caucasians, highlighting Asian hair's lower density and thicker dermis, and reports no new research findings.
14 citations
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December 2010 in “Journal of human genetics” This study identified a severe MBTPS2 gene mutation in a Japanese patient with IFAP syndrome, suggesting other factors may influence the varied clinical severity of the condition.
May 2026 in “Archives of Dermatological Research” This review discusses the psychological and economic impact of alopecia areata in Asia, highlighting significant quality of life reductions and a substantial financial burden on patients without providing new clinical results.
7 citations
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March 2000 in “CRC Press eBooks” 7 citations
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August 2024 in “Clinical and Experimental Dermatology” In this retrospective study conducted at a trichology clinic, the off-label use of upadacitinib for at least 24 weeks was found to have a promising efficacy and safety profile for treating severe alopecia areata in adolescents.
1 citations
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February 2023 in “Pediatric Dermatology” This case report of an infant with IPEX syndrome highlights the importance of early recognition and treatment, as the patient experienced severe symptoms and succumbed before stem cell transplantation.
January 2026 in “Applied Biological Chemistry” This study found that Ishophloroglucin A from brown seaweed may treat androgenic alopecia by inhibiting 5α-reductase and promoting hair growth-related factors in human dermal papilla cells.
In this study, researchers successfully cloned the KAP24.1 gene from sheep to analyze its expression in skin and hair follicles, finding that Mountain-type Hetian sheep showed the highest levels of expression and that androgen concentration significantly influenced KAP24.1 protein expression.
January 2013 in “Shiyong yixue zazhi” In this study with mouse follicle stem cells, astraglus polysaccharide increased markers of cell proliferation and gene expression, suggesting a potential mechanism for treating alopecia and promoting hair growth.
1 citations
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January 2023 in “The FASEB Journal” This study found that circAGK was highly expressed in AGA patients and promoted dermal papilla cell apoptosis, suggesting it as a potential target for treating androgen alopecia.
13 citations
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April 1994 in “Journal of Investigative Dermatology” Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
33 citations
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November 2020 in “AAPS PharmSciTech” 38 citations
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September 2017 in “Journal of zoo and wildlife medicine” This study describes the successful management of Andean bear alopecia syndrome in three female bears using oclacitinib, leading to rapid pruritus resolution and fur regrowth without adverse effects.
January 2019 in “Journal of Case Reports and Scientific Images” This case report describes the treatment of a 12-year-old female with Alopecia Areata using oral azathioprine.
December 2025 in “JURNAL PIJAR MIPA” This study explored the Belanger tradition, a Sasak hair-cleansing ritual using natural ingredients, and concluded that it combines cultural heritage with sustainable practices and scientifically supported benefits.
In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.
1 citations
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October 2021 in “International Journal of Research in Dermatology” This study found that alopecia areata can affect individuals across various ages but is predominantly observed in males aged 21-40, and may be linked to autoimmune diseases, thyroid issues, and inflammation.
10 citations
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May 2000 in “PubMed” This study found that the prevalence of male androgenetic alopecia in a Singapore community was 63%, increasing with age and showing higher rates among Indians compared to Chinese.
September 2025 in “Intisari Sains Medis” This case report from this study demonstrates the potential of treating severe alopecia areata with a combination of microneedling, minoxidil, desoximetasone, and methylprednisolone, noting initial hair regrowth after 14 days but emphasizing the need for further research to confirm long-term efficacy and safety.
September 2023 in “International Journal of Dermatology” In this study, FAPD was characterized in a Chinese population by perifollicular mast cell infiltration, suggesting young individuals may be at higher risk than previously thought.
August 2023 in “Health Sciences and Pharmacy Journal” In this review, researchers identified 10 natural plants, including candlenut and clove, that have shown potential to inhibit alopecia progression and stimulate hair growth due to their diverse phytochemical and pharmacological properties in vitro and in vivo.
22 citations
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June 2012 in “Journal of Investigative Dermatology” This study found that adiponectin promotes hair growth in cultured human hair follicles, suggesting its receptors could be a target for clinical hair growth strategies.
January 2025 in “SKIN The Journal of Cutaneous Medicine” People with alopecia areata face different healthcare access and experiences based on their race and ethnicity.
10 citations
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May 2018 in “Cell death discovery” This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.
July 2026 in “Journal of the American Academy of Dermatology”
19 citations
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June 2002 in “American Journal of Dermatopathology” This study found significant differences in bcl-2 expression between areas of the scalp affected and unaffected by androgenetic alopecia, suggesting a uniform follicle population or synchronized follicular cycling in affected areas.