Microneedling Combination With 5% Minoxidil and Systemic and Topical Steroids in Alopecia Areata Patients: Case Report

    September 2025 in “ Intisari Sains Medis ”
    I Gusti Ayu Agung Mini Laksmi, Ketut Kwartantaya Winaya, Gusti Ayu Anggawati, Michael Hostiadi
    From the encyclopedia
    Microneedling →

    technique to create small wounds in skin to activate collagen production and hair growth

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Desoximetasone →
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    Studysummary This case report from this study demonstrates the potential of treating severe alopecia areata with a combination of microneedling, minoxidil, desoximetasone, and methylprednisolone, noting initial hair regrowth after 14 days but emphasizing the need for further research to confirm long-term efficacy and safety. Our plain-language summary of this paper — not a Tressless recommendation.
    This case report highlights the potential of a combination therapy involving microneedling, 5% minoxidil, desoximetasone, and methylprednisolone for treating severe alopecia areata (AA) in a 24-year-old male patient. The patient showed improvement after 14 days of treatment, indicating the therapy's initial effectiveness. However, the report emphasizes the need for further evidence through serial measurements to fully assess the efficacy and safety of this treatment approach.
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