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Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Keratins are important for skin cell health and their problems can cause diseases.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Prolactin slows down hair growth in mice.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Finasteride improves hidradenitis suppurativa but not for child-bearing women.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Scientists found cells in hair that are key for growth and color.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.