research Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss
Spironolactone helps regrow hair in women with hair loss.
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research Antiandrogen Therapy for Androgenetic Alopecia
Antiandrogen therapy helps treat genetic hair loss.
research Effects of Flutamide, a Pure Antiandrogen, on Endocrine Parameters in the Adult Female Rat
Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research The Association of Cytosine-Adenine-Guanine Repeat Polymorphism in the Androgen Receptor Gene with Nodulocystic Acne in Egyptian Patients
Certain gene variations are linked to severe acne in Egyptian patients and could guide treatment choices.
research Study of the Expression of Androgen, Estrogen, and Progesterone Receptors in Patients With Frontal Fibrosing Alopecia
The study suggests a possible increase in androgen receptors in patients with frontal fibrosing alopecia, but more research is needed.
research RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia, and Hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.
research Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research The Antiandrogenic Effect of Finasteride Against a Mutant Androgen Receptor
Finasteride may improve prostate cancer treatment outcomes.
research Significance of RU58841 as a Therapeutic Agent Affecting Androgen Receptor Molecular Interactions in Human Hair Follicles
RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
research Synthesis and Structure–Activity Studies of Side-Chain Derivatized Arylhydantoins for Investigation as Androgen Receptor Radioligands
The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
research Antiandrogen Therapy for Skin and Hair Disease
Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.
research Cortexolone 17α-Propionate (Clascoterone) Is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro
Clascoterone may be an effective topical treatment for hair loss.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Hidradenitis Suppurativa: An Androgen-Dependent Disorder
Hidradenitis suppurativa improves with antiandrogen therapy.
research Structural Perspectives on the Androgen Receptor, the Elusive Shape-Shifter
The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.
research The Role of Androgens in Hidradenitis Suppurativa and the Potential Benefits of Antiandrogen Therapy
Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
research Hospitalists for the NHS: The Role of Androgens and Antiandrogen Therapy in Hidradenitis Suppurativa
Antiandrogen therapy may help treat hidradenitis suppurativa.
research Treatment of Female Pattern Hair Loss With Oral Antiandrogens
Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.
research Characteristics of Flutamide Action on Prostatic and Testicular Functions in the Rat
Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
research RU 58841-Myristate Prodrug Development for Topical Treatment of Acne and Androgenetic Alopecia
RUM-loaded SLN shows promise for treating acne and hair loss topically.
research Demographics of Women with Female Pattern Hair Loss and the Effectiveness of Spironolactone Therapy
Spironolactone may effectively treat female hair loss, especially with hyperandrogenism signs.
research Becker Nevus Syndrome
The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.
research Update on Idiopathic Hirsutism: Diagnosis and Treatment
The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
research Trends in the Prescribing Pattern of Spironolactone for Acne and Hidradenitis Suppurativa in Adolescents
Doctors are prescribing spironolactone more often to treat acne and skin conditions in teenagers, and it seems safe and well-tolerated.
research TMPRSS2, Required for SARS-CoV-2 Entry, Is Downregulated in Lung Cells by Enzalutamide, a Prostate Cancer Therapeutic
A prostate cancer drug can lower the levels of a protein that the coronavirus uses to enter lung cells.
research Antihormonal Properties of Some New A-Homo-B, 19-Dinor Steroids of the Androstane Series
New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.
research Causes and Management of Hair Loss in Women
The document concludes that hair loss in women can be caused by various factors and is managed with specific treatments like medication, therapy, and lifestyle changes.
research Female Androgenetic Alopecia
Female pattern hair loss is different from male pattern hair loss and has unclear genetic causes.
research Breakthroughs in the Diagnosis and Treatment of Male and Female Pattern Hair Loss
New methods can diagnose hair loss by examining the scalp and can treat it with a mix of oral and topical medications, along with cosmetic procedures like hair transplants.