Female Androgenetic Alopecia

    Andrew G. Messenger, Silke Redler, Regina C. Betz
    TLDR Female pattern hair loss is different from male pattern hair loss and has unclear genetic causes.
    The article discussed the complexities of female androgenetic alopecia (AGA) and questioned whether it should be considered the same condition as male AGA. While both conditions share similarities in histopathology and prevalence with age, significant differences exist in their etiology. Genetic studies have shown a strong genetic component in male AGA, but evidence for a genetic basis in female AGA is weak. Some studies suggested a weak association with the estrogen receptor gene ESR2, but overall, the genetic contribution to female AGA remains unclear. The article proposed using the term "Female Pattern Hair Loss" instead of "female AGA" to better reflect the multifactorial nature of the condition, which includes environmental and hormonal factors. The effectiveness of antiandrogen treatments in women is still controversial, with mixed results from clinical trials.
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