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The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.

Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.

DHT may reduce inflammation caused by certain bacteria in skin cells.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Finasteride and GIZh-72 reduce inflammation, with GIZh-72 being more effective.

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.

Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

*Acorus calamus* has many medicinal benefits but needs more safety research.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

New acne treatments show promise as alternatives to traditional therapies.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.