March 2026 in “Konuralp Tıp Dergisi” This study found that participants with normal hemoglobin but low ferritin experienced significantly more symptoms like restless leg syndrome, dizziness, and shortness of breath compared to those with normal ferritin.
17 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that anthralin and mechlorethamine were the most effective therapies among those tested in AA-affected rodent models, providing a basis for further analysis of their mechanisms in Alopecia Areata.
5 citations
,
June 2002 in “Clinical and Experimental Dermatology” This presentation reviews the management of alopecia areata, emphasizing treatment challenges and options, but reports no new clinical results.
32 citations
,
January 1971 in “Annals of Internal Medicine” This study observed that severe bronchitis may occur in individuals with anhidrotic ectodermal dysplasia when exposed to a dusty environment, potentially due to abnormalities in the bronchial mucosa.
4 citations
,
November 2015 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This case study highlights a patient with alopecia areata who also has eosinophilic esophagitis, suggesting it may be considered an atopic disease and a potential trigger for alopecia areata in affected patients.
84 citations
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October 2007 in “The Journal of Immunology” This study found that chronic eczema supports the expansion of myeloid suppressor cells, which contribute to silencing autoreactive T cells and partially promote hair regrowth in alopecia areata.
1 citations
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January 2021 in “Dermatologic Therapy” This study found that intralesional Candida antigen was as effective as intralesional steroids for treating alopecia areata after 5 months, with significantly lower injection pain reported in the Candida group.
March 2026 in “JID Innovations” In a mouse model study, researchers found that mutations in Aire reduced alopecia areata frequency, while Notch4 mutations did not lead to the disease, likely due to proximity with a resistance gene.
April 2016 in “Journal of The American Academy of Dermatology” People with certain allergic conditions or higher white blood cell counts have more severe hair loss, and treating hair and nail side effects early in melanoma therapy can improve quality of life.
April 2023 in “Journal of Investigative Dermatology” This review found that while about 60% of patients with alopecia areata responded to liquid nitrogen cryotherapy in existing studies, no significant efficacy difference was observed compared to intralesional steroid injections, though relapse rates may be lower with cryotherapy.
29 citations
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December 2022 in “Dermatology and Therapy” This study reported that patients with alopecia areata experienced significant increases in work productivity loss and activity impairment due to worsening emotional symptoms, highlighting a need for better treatments.
23 citations
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September 2017 in “Journal of the American Academy of Dermatology” This article hypothesizes that apremilast, a phosphodiesterase 4 inhibitor, could be a targeted treatment for alopecia areata due to its ability to suppress interferon-gamma production, but reports no new clinical results.
10 citations
,
August 2011 in “Clinics” This article presents a dissenting opinion, arguing that the case described by Dr. Molina et al. was diffuse alopecia areata, not acute alopecia areata as claimed, emphasizing the importance of distinct clinical differences.
January 2025 in “Dermatologic Therapy” This study found that nonablative Er:YAG laser therapy effectively improved hair appearance for patients with androgenetic alopecia, with most participants reporting increased satisfaction and no adverse reactions, following six biweekly sessions.
November 2025 in “Skin Health and Disease” This study found that patients with alopecia areata had a higher prevalence of depression, anxiety, and alexithymia compared to normative data, with alexithymia more common in those with earlier onset AA, lower education levels, and younger age.
October 2024 in “Annals of Allergy Asthma & Immunology” This case study reports on a 4-year-old girl who developed telogen effluvium, a type of hair loss, after experiencing anaphylactic reactions to cow's milk. The authors highlight this as the first documentation of anaphylaxis potentially triggering telogen effluvium due to physiologic stress.
2 citations
,
December 2001 in “Dermatologic Therapy” This study found elevated unoccupied type II GC receptors and decreased thioredoxin levels in alopecia areata patients' scalps, which may explain the variable effectiveness of glucocorticoid treatment for hair regrowth.
11 citations
,
January 1976 in “Dermatology” This study found that patients with alopecia areata atopica and other skin conditions had lower hair magnesium levels compared to healthy controls, although the differences largely overlapped.
43 citations
,
May 1999 in “Journal of Biological Chemistry” This study found that full-length Agouti protein modulates melanocortin receptor signaling through a dual mechanism involving competitive antagonism and receptor down-regulation, whereas the carboxyl-terminal fragment acts solely as a competitive antagonist.
April 2016 in “Journal of The American Academy of Dermatology” A child on life support experienced rapid hair loss due to severe illness affecting hair growth.
June 2025 in “Academic Medical Journal” This review discusses the mechanisms underlying the collapse of hair follicle immune privilege in alopecia areata and emphasizes the importance of therapeutic strategies aimed at restoring immune tolerance.
July 2022 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
2 citations
,
May 2023 in “The Journal of Immunology” This animal study observed that treatment with the S1PR modulator NXC736 significantly reduced lesion area and CD8+ T cell infiltration in mice with alopecia areata, suggesting its potential as a promising therapy for the condition.
43 citations
,
March 2011 in “Journal of psychosomatic research” This study found that children with alopecia areata experienced more stressful life events and excreted higher levels of catecholamines compared to healthy siblings.
50 citations
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March 2000 in “American Journal of Clinical Dermatology” This article discusses the etiology, clinical features, and treatment of alopecia areata but presents no new clinical findings, underlining the palliative nature of current therapies.
August 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses identifying and preventing iron deficiency anemia but provides no new clinical findings.
12 citations
,
August 2013 in “Journal of Dermatological Science” This article shares the researchers' challenging journey in exploring the pathobiology of alopecia areata and reports no definitive clinical advances.
15 citations
,
February 2013 in “Journal of Clinical Medicine and Research” The researchers reported that both cryotherapy and betamethasone lotion yielded similar improvement rates for alopecia areata patches, without complete recovery observed in any patient.
1 citations
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January 2025 in “Discrete and Continuous Dynamical Systems - B” This study developed and analyzed a mathematical model for alopecia areata involving interactions among immune cells and cytokines, establishing conditions under which hairless patches can become stable and pervasive, particularly with certain biological rate levels and chemotactic sensitivities.
November 2025 in “Allergologia et Immunopathologia” This case report documents a rare incident where total alopecia developed within ten days of a bee sting, in the absence of hypersensitivity reactions, suggesting that bee venom may have an immunomodulatory or exacerbating effect on the immune system.