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Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Diane 35 plus finasteride is more effective for treating hirsutism.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.