May 2025 in “Antioxidants” This review highlights how natural products with antioxidant properties can modulate the Wnt signaling pathway, potentially influencing various pathological conditions such as cancer, stroke, and regenerative medicine. It also addresses controversies in the compounds' mechanisms across different models and suggests research directions for future studies.
January 2025 in “Journal of Applied Pharmaceutical Science” This study examined the effectiveness of peppermint essential oil formulated into a nanoliposome gel for enhancing hair growth, finding that this preparation increased hair growth in male Sprague Dawley rats without causing irritation, suggesting it may improve delivery of these active ingredients.
May 2024 in “Pharmacia/Farmaciâ” In this study, Ipomoea batatas leaf extracts exhibited significant hair growth stimulation and strong antifungal activity against Malassezia furfur, potentially offering a promising treatment for alopecia with further research needed on their androgen receptor inhibition potential.
May 2024 in “Academia Open” In this study, conducted on male Wistar rats, high doses of white turi flower extract significantly increased sodium and potassium kidney levels, causing symptoms like lethargy and hair loss without fatalities, suggesting potential acute toxicity that warrants further research for long-term safety assessment.
March 2024 in “International journal of pharmaceutical and bio-medical science (Print)” This review examines Angelica sinensis and Chinese arborvitae, highlighting their historical and contemporary use in traditional Chinese medicine and pharmacology. It emphasizes the need for more comprehensive scientific assessments to fully explore their therapeutic potential.
July 2023 in “Research journal of pharmacy and technology” In this study on male rabbits, a hair tonic formulated with delipidated ethanol extract of Capsicum frutescens L. leaves at concentrations of 5%, 10%, and 20% promoted hair growth more effectively than a placebo and similar to 2% Minoxidil at the highest concentration.
January 2021 in “Systematic Reviews in Pharmacy” This study found that 90% of pregnant women experience physiological skin changes, with Striae Gravidarum being the most common, especially in multigravid individuals.
May 2023 in “Endocrine, metabolic & immune disorders” This review describes the diverse pharmacological and phytochemical properties of Hibiscus rosa-sinensis, noting its wide range of traditional medicinal uses and safety at higher extract doses.
34 citations
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November 2023 in “Applied Materials Today” This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.
1 citations
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February 2023 in “Plant disease” This study reports the first identification of 'Candidatus Phytoplasma aurantifolia' in the invasive weed Eclipta prostrata in Taiwan, linked to symptoms such as branch proliferation and phyllody.
8 citations
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April 2019 in “International journal of scientific research in biological science” This review discusses the natural habitat, taxonomy, phytochemical components, pharmacological activities, and potential medical applications of Tridax procumbens but reports no new experimental findings.
August 2025 in “Journal of the Korean Society of Cosmetology” In this study, a 5% Gymnema sylvestre leaf extract formulation applied to C3H mice showed significantly delayed hair regrowth by increasing TGF-β1 and TGF-β2 expression while reducing β-catenin levels, suggesting its potential as a natural hair growth inhibitor.
October 2021 in “Research Society and Development” This review discusses potential drug interactions between herbal medicines and oral contraceptives, reporting no new research results but highlighting the risk these interactions pose to contraceptive effectiveness.
November 2024 in “International Journal of Plant and Environment” This study analyzed Sphenodesme involucrata var. paniculata leaves and found high carbohydrate and calcium content, along with several bioactive compounds, supporting their use in traditional medicine for their nutrient-rich properties.
In this study, researchers used an integrated in silico approach to demonstrate that Polygonum multiflorum combats androgenetic alopecia via anthraquinone emodin, which targets PI3K catalytic subunits differently from traditional antiandrogenic treatments, showing potential as a novel therapeutic strategy.
This study reported that acupuncture combined with topical Aloe vera and celery gel reduced hair loss from alopecia androgenetica after 28 days of treatment.
1 citations
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January 2019 in “Zenodo (CERN European Organization for Nuclear Research)” This anatomical study on Eclipta alba concluded that unique secretory structures in stems and leaves may serve as identifying features of the plant and the Asteraceae family.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
5 citations
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November 2017 in “Asian journal of pharmaceutical and clinical research” This study found that water fractions of Angiopteris evecta stimulated hair growth in male rabbits, suggesting potential alopecia treatment benefits pending further research in humans.
November 2021 in “Skin appendage disorders” This case report describes the first known instances of male androgenetic alopecia with trichoteiromania, suggesting self-induced hair loss can occur alongside patterned miniaturization of hair.
September 2021 in “CRC Press eBooks” This review discusses the diagnostic features of androgenetic alopecia through trichoscopy and reports no clinical results; it emphasizes hair shaft variability and yellow dots as key indicators.
September 2024 in “Journal of Ethnopharmacology” In this study, Terminalia bellirica extracts promoted hair regrowth in testosterone-induced AGA mice, possibly by inhibiting type II 5α-reductase activity and enhancing the MAPK signaling pathway.
January 2023 in “Dermatologic Therapy” This study demonstrates a significant correlation between anxiety, depression, and reduced quality of life in individuals with androgenetic alopecia.
13 citations
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October 2004 in “Anais Brasileiros De Dermatologia” This article reviews various self-aggressive hair disorders such as trichotillomania and emphasizes the psychiatric aspects of these conditions, but reports no new clinical findings.
March 2026 in “International Journal of Science and Research (IJSR)” This research focused on Eclipta prostrata, revealing unique anatomical features and bioactive compounds such as alkaloids and flavonoids that can aid in reliable identification and quality control of this medicinal herb, commonly used for hair growth and liver health.
11 citations
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June 2017 in “Journal of cell science” In this study, researchers found that AGD1 is crucial for membrane recruitment during root hair development in Arabidopsis thaliana, with its pleckstrin homology domain essential for targeting specific plasma membrane regions.
29 citations
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February 2019 in “Pediatric dermatology” This abstract suggests that specific trichoscopic features like black dots, coiled hair, and trichoptilosis may help differentiate trichotillomania from patchy alopecia areata.
4 citations
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January 2020
September 2025 in “Media Kedokteran Hewan” This study found that 90% of African pygmy hedgehogs at Golden Dhonje Farm in Bogor District were affected by potential zoonotic fungi, including Scopulariopsis sp. and Penicillium sp.