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Hormonal therapies like cyproterone acetate and spironolactone may help some women with hair loss, but finasteride 1mg is not useful, and the effectiveness of other treatments is still unclear.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Feathers are useful for researching growth, regeneration, and the effects of treatments like chemotherapy on hair loss.

The dog with an Alopecia Areata-like condition showed signs of an autoimmune disease and partially regrew hair without treatment, suggesting dogs could be models for human AA research.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.

Melatonin may help manage PCOS by improving insulin sensitivity, hormone balance, and mood.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Scientists made a mouse that can be made to lose hair and then grow it back.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.

The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.

Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.