research Pharmacokinetics of a Transdermal Testosterone Cream in Healthy Postmenopausal Women
A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
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research Medical Treatment of Hirsutism in Women
Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.
research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Exclusive Androgenic Effect of Dehydroepiandrosterone in Sebaceous Glands of Rat Skin
DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage: An Experimental Animal Study
Finasteride may cause kidney damage.
research Hirsuties
Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
research Comprehensive Transcriptome Profiling of Balding and Non-Balding Scalps in Trichorhinophalangeal Syndrome Type I Patient
The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.
research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy
Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue
KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.
research Protective Trend of Anti-Androgen Therapy During the COVID-19 Pandemic: A Meta-Analysis
Anti-androgen therapy might help protect against COVID-19 infection and reduce death risk.
research Epidemiological Assessment of Testosterone Levels in Women: A Factorial Analysis of Cell Proliferation
High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
research Low Anabolic Profile in Assessing a Patient’s Overall Hair Loss
Some supplements and hormones can increase hair loss by raising DHT levels.
research Signaling Pathways and Targeted Therapeutic Strategies for Polycystic Ovary Syndrome
Effective PCOS treatments require targeting specific signaling pathways.
research Effects of Androgen Treatment on Growth in Patients with 5-Alpha-Reductase Type 2 Deficiency
Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Nociceptive and Non-Nociceptive Roles of TRPV3 and Its Druggability
TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
research 28-Year-Old Woman with Hyperprolactinemia and Its Relationship to Polycystic Ovary Syndrome
Treating hyperprolactinemia can help manage PCOS symptoms.
research Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis Explaining Paradoxical Results
5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
research Hair Replacement Surgery for Male Pattern Alopecia
Surgical hair replacement is a viable option for male pattern baldness when done with proper planning and realistic expectations.
research The Biology of Hair Growth
Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
research Clinical Applications of Antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
research Androgenetic Alopecia And Hair Growth Promotion: Present And Future
Current research explores hair growth drugs, while future research aims for personalized treatments.
research In Vivo Uptake and Metabolism of Testosterone by the Skin and Other Tissues of the Rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
research Hair Loss in Women: Comprehensive Overview and Treatment Options
Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.
research Anti-Androgenic Curcumin Analogues as Steroid 5-Alpha Reductase Inhibitors
Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
research Bisphenol-A Antagonizes the Rapidly Modulating Effect of Dihydrotestosterone on Spinogenesis and Long-Term Potentiation of Hippocampal Neurons
Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.