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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Androgen use may increase the risk of stroke, but more research is needed.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.

New drug shows promise for better hair growth in baldness treatment.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Effective PCOS treatments require targeting specific signaling pathways.

PCOS may increase the risk of certain cancers.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.