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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

High-dose androgen therapy can help manage certain types of androgen resistance.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

AR polyglycine repeat doesn't cause baldness.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Reduced AR gene methylation may cause early pubic hair growth in girls.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

G allele of AR Stul polymorphism linked to higher hair loss risk, especially in white people.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.