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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

Balding men have harder scalps.

Certain genes influence immunoglobulin levels in Chinese Holstein cows, which can improve calf health.

Selective breeding can enhance immunity in dairy cattle.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.

The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.

The supplement may help hair growth and is safe, but more research is needed.

Thyroid hormone receptors are essential for hair growth and wound healing.

Allopregnanolone changes gene expression in glioblastoma cells.

A specific genetic marker is linked to male pattern baldness in Han Chinese men.

Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.

Immune activities and specific genes are important in male pattern baldness.

Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.

Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Researchers found 15 new genetic links to skin traits in Japanese women.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.