Search
for
Sort by
Research
30-60 / 1000+ results![Molecular genetics of androgen insensitivity](/images/research/619d7e8f-7be1-4cb7-bafe-c882c95c8dbf/small/20529.jpg)
research Molecular genetics of androgen insensitivity
Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
research Uromedic® Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor <em>in Vitro</em>
Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.
![Anti-Androgen Effects of Extracts and Compounds from<i>Ganoderma lucidum</i>](/images/research/1fe8b562-fcd5-4f89-b6a0-a487094cf0a3/small/15010.jpg)
research Anti-Androgen Effects of Extracts and Compounds fromGanoderma lucidum
Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
![Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer](/images/research/57e0759a-11fc-4c67-a4c8-0ee8dd7756aa/small/36016.jpg)
research Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
![Androgenetic Alopecia: A Chronic or Pubertal Onset Disease Retarded by Blood Donation](/images/research/0235142c-e41b-4770-b07f-678b54679b6a/small/4114.jpg)
research Androgenetic Alopecia: A Chronic or Pubertal Onset Disease Retarded by Blood Donation
Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.
![Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne](/images/research/0d73b3c0-60f4-42a1-bdc8-1a3416de135d/small/2193.jpg)
research Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne
Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.
![Chapter 17. Selective androgen receptor modulators (SARMs)](/images/research/3d149d1d-93f2-4893-9a14-e2c1502d9a06/small/12609.jpg)
research Chapter 17. Selective androgen receptor modulators (SARMs)
Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
![Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes](/images/research/e28aa5c8-2caf-435f-880a-dce93bab2c1c/small/28118.jpg)
research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
![A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity](/images/research/4fca6c7a-15bb-4b29-ac99-93890fc4043b/small/20447.jpg)
research A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
![Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia](/images/research/fb237c2c-5c29-4419-97ff-693bf2e857bf/small/5110.jpg)
research Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
![Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia](/images/research/db53d0bd-3a65-437c-80c2-28b1a47e3bd4/small/2479.jpg)
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
![Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases](/images/research/b462824e-f94c-459b-809e-72dbf27e203e/small/13950.jpg)
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
![Anti-androgens for the treatment of hirsutism](/images/research/41a68120-5ff8-49e6-976f-302a17c84c6a/small/28174.jpg)
research Anti-androgens for the treatment of hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
![Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women](/images/research/fe399dd0-cd41-4109-b3b0-69032311536e/small/32635.jpg)
research Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
![Bad Hair Day: Testosterone and Wnts](/images/research/7489412e-acd0-4881-9cf7-c99258c79c33/small/14286.jpg)
research Bad Hair Day: Testosterone and Wnts
Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
![Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies](/images/research/78e9ec1f-4866-42ac-8c9e-e213074b35de/small/4898.jpg)
research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
Hormones and genes affect hair growth and male baldness.
![Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection](/images/research/fae43a12-b27a-4d2b-ac6f-d4988ebc7726/small/14217.jpg)
research Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection
RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.
![Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene](/images/research/ba0d446a-cb8c-42c6-a074-49eec728afe1/small/32638.jpg)
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
![Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications](/images/research/5588b222-0774-4dfc-aa6b-a2a51029f470/small/28092.jpg)
research Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications
Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
![Circulating and intraprostatic sex steroid hormonal profiles in relation to male pattern baldness and chest hair density among men diagnosed with localized prostate cancers](/images/research/78509109-c8d8-4d9c-8ff6-6e029658324e/small/13799.jpg)
research Circulating and intraprostatic sex steroid hormonal profiles in relation to male pattern baldness and chest hair density among men diagnosed with localized prostate cancers
Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
![Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life](/images/research/e27f8541-2233-4bc9-b01f-281111b6d5c6/small/18012.jpg)
research Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life
Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
![Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders](/images/research/b4b58156-99a6-405d-ac6a-f4cb11425adf/small/20558.jpg)
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Role of insulin, insulin‐like growth factor‐1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris
Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
![Androgen Effects in Mammals](/images/research/4660fbe2-4d09-473d-b4e8-d592778472ec/small/15421.jpg)
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
![Immunocytochemical Localization of Androgen Receptors in the Scalp of the Stumptail Macaque Monkey, a Model of Androgenetic Alopecia](/images/research/b9b6449f-806c-4edf-a450-e50491554c2d/small/2031.jpg)
research Immunocytochemical Localization of Androgen Receptors in the Scalp of the Stumptail Macaque Monkey, a Model of Androgenetic Alopecia
Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
![Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline](/images/research/2254a31a-f7c4-4952-9e76-5180158f50f3/small/20990.jpg)
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
![Androgen Conjugates: Physiology and Clinical Significance](/images/research/67c8e8f2-a2c6-4aaa-a117-d4436176e596/small/28256.jpg)
research Androgen Conjugates: Physiology and Clinical Significance
Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.
![Androgen regulation of a specific gene in hamster flank organs](/images/research/7081e49f-df95-4670-91e5-bbd3c7a1ede4/small/28260.jpg)
research Androgen regulation of a specific gene in hamster flank organs
Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
![Markers of peripheral androgen action in vivo and in vitro](/images/research/7883872b-c478-4625-929f-1f292adaa563/small/21163.jpg)
research Markers of peripheral androgen action in vivo and in vitro
Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.