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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Certain drugs that block specific enzymes can help treat prostate diseases.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride may cause kidney damage.

Men who start balding at age 20 may have a higher chance of getting aggressive prostate cancer.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.